The effect of COVID-19 vaccines on sperm parameters: a systematic review and meta-analysis
Published data were gathered for a meta-analysis to determine the difference in sperm parameters before and after administration of different types of coronavirus disease 2019 (COVID-19) vaccines, because the reproductive toxicity of COVID-19 vaccines has not yet been evaluated in clinical trials an...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2023-01-01
|
| Series: | Asian Journal of Andrology |
| Subjects: | |
| Online Access: | http://www.ajandrology.com/article.asp?issn=1008-682X;year=2023;volume=25;issue=4;spage=468;epage=473;aulast= |
| _version_ | 1797738861604896768 |
|---|---|
| author | Yu-Cheng Ma Chao Cheng Chi Yuan Li-Yuan Xiang Jun Wen Xi Jin |
| author_facet | Yu-Cheng Ma Chao Cheng Chi Yuan Li-Yuan Xiang Jun Wen Xi Jin |
| author_sort | Yu-Cheng Ma |
| collection | DOAJ |
| description | Published data were gathered for a meta-analysis to determine the difference in sperm parameters before and after administration of different types of coronavirus disease 2019 (COVID-19) vaccines, because the reproductive toxicity of COVID-19 vaccines has not yet been evaluated in clinical trials and COVID-19 has been associated with decreases in sperm quality. The preferred procedures for systematic reviews and meta-analyses were followed in the conduct and reporting of this study. The average sperm parameters of all sperm donors' multiple sperm donations were compared before and after receiving various COVID-19 vaccinations. Semen volume, total sperm motility, total sperm count, morphological change, and sperm concentration were the primary outcome measures. We compiled and analyzed the results of six studies on total sperm motility, six studies on semen volume, six studies on sperm concentration, two studies on morphological change, and two studies on total sperm count. Parameter comparisons with patients who had and had not been vaccinated were only reported in one of the included studies. When different types of COVID-19 vaccine injections were compared, no discernible differences in parameters were observed. According to the available data, the parameters of semen are unaffected by inactivated or messenger RNA (mRNA) COVID-19 vaccinations. To support these findings, additional prospectively designed research is required. |
| first_indexed | 2024-03-12T13:49:00Z |
| format | Article |
| id | doaj.art-62a77366c03f473697b2b585fe59dcd2 |
| institution | Directory Open Access Journal |
| issn | 1008-682X 1745-7262 |
| language | English |
| last_indexed | 2024-03-12T13:49:00Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Asian Journal of Andrology |
| spelling | doaj.art-62a77366c03f473697b2b585fe59dcd22023-08-23T07:27:55ZengWolters Kluwer Medknow PublicationsAsian Journal of Andrology1008-682X1745-72622023-01-0125446847310.4103/aja2022100The effect of COVID-19 vaccines on sperm parameters: a systematic review and meta-analysisYu-Cheng MaChao ChengChi YuanLi-Yuan XiangJun WenXi JinPublished data were gathered for a meta-analysis to determine the difference in sperm parameters before and after administration of different types of coronavirus disease 2019 (COVID-19) vaccines, because the reproductive toxicity of COVID-19 vaccines has not yet been evaluated in clinical trials and COVID-19 has been associated with decreases in sperm quality. The preferred procedures for systematic reviews and meta-analyses were followed in the conduct and reporting of this study. The average sperm parameters of all sperm donors' multiple sperm donations were compared before and after receiving various COVID-19 vaccinations. Semen volume, total sperm motility, total sperm count, morphological change, and sperm concentration were the primary outcome measures. We compiled and analyzed the results of six studies on total sperm motility, six studies on semen volume, six studies on sperm concentration, two studies on morphological change, and two studies on total sperm count. Parameter comparisons with patients who had and had not been vaccinated were only reported in one of the included studies. When different types of COVID-19 vaccine injections were compared, no discernible differences in parameters were observed. According to the available data, the parameters of semen are unaffected by inactivated or messenger RNA (mRNA) COVID-19 vaccinations. To support these findings, additional prospectively designed research is required.http://www.ajandrology.com/article.asp?issn=1008-682X;year=2023;volume=25;issue=4;spage=468;epage=473;aulast=covid-19; mrna vaccine; sperm parameters; sperm quality; vaccine safety |
| spellingShingle | Yu-Cheng Ma Chao Cheng Chi Yuan Li-Yuan Xiang Jun Wen Xi Jin The effect of COVID-19 vaccines on sperm parameters: a systematic review and meta-analysis Asian Journal of Andrology covid-19; mrna vaccine; sperm parameters; sperm quality; vaccine safety |
| title | The effect of COVID-19 vaccines on sperm parameters: a systematic review and meta-analysis |
| title_full | The effect of COVID-19 vaccines on sperm parameters: a systematic review and meta-analysis |
| title_fullStr | The effect of COVID-19 vaccines on sperm parameters: a systematic review and meta-analysis |
| title_full_unstemmed | The effect of COVID-19 vaccines on sperm parameters: a systematic review and meta-analysis |
| title_short | The effect of COVID-19 vaccines on sperm parameters: a systematic review and meta-analysis |
| title_sort | effect of covid 19 vaccines on sperm parameters a systematic review and meta analysis |
| topic | covid-19; mrna vaccine; sperm parameters; sperm quality; vaccine safety |
| url | http://www.ajandrology.com/article.asp?issn=1008-682X;year=2023;volume=25;issue=4;spage=468;epage=473;aulast= |
| work_keys_str_mv | AT yuchengma theeffectofcovid19vaccinesonspermparametersasystematicreviewandmetaanalysis AT chaocheng theeffectofcovid19vaccinesonspermparametersasystematicreviewandmetaanalysis AT chiyuan theeffectofcovid19vaccinesonspermparametersasystematicreviewandmetaanalysis AT liyuanxiang theeffectofcovid19vaccinesonspermparametersasystematicreviewandmetaanalysis AT junwen theeffectofcovid19vaccinesonspermparametersasystematicreviewandmetaanalysis AT xijin theeffectofcovid19vaccinesonspermparametersasystematicreviewandmetaanalysis AT yuchengma effectofcovid19vaccinesonspermparametersasystematicreviewandmetaanalysis AT chaocheng effectofcovid19vaccinesonspermparametersasystematicreviewandmetaanalysis AT chiyuan effectofcovid19vaccinesonspermparametersasystematicreviewandmetaanalysis AT liyuanxiang effectofcovid19vaccinesonspermparametersasystematicreviewandmetaanalysis AT junwen effectofcovid19vaccinesonspermparametersasystematicreviewandmetaanalysis AT xijin effectofcovid19vaccinesonspermparametersasystematicreviewandmetaanalysis |