The Helicase PIF1 Facilitates Resection over Sequences Prone to Forming G4 Structures
Summary: DNA breaks are complex lesions that can be repaired either by non-homologous end joining (NHEJ) or by homologous recombination (HR). The decision between these two routes of DNA repair is a key point of the DNA damage response (DDR) that is controlled by DNA resection. The core machinery ca...
Main Authors: | Sonia Jimeno, Rosa Camarillo, Fernando Mejías-Navarro, Maria Jesús Fernández-Ávila, Isabel Soria-Bretones, Rosario Prados-Carvajal, Pablo Huertas |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2018-09-01
|
Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124718313330 |
Similar Items
-
Structural Studies of Pif1 Helicases from Thermophilic Bacteria
by: Stéphane Réty, et al.
Published: (2023-02-01) -
Direct quantification of the translocation activities of Saccharomyces cerevisiae Pif1 helicase
by: Lu, Chen, et al.
Published: (2020) -
DNA helicase PIF1 regulates cell proliferation and DNA damage in ovarian cancer
by: ZHOU Qiyin, et al.
Published: (2024-12-01) -
Mechanistic Insight Into Cadmium- and Zinc-Induced Inactivation of the Candida albicans Pif1 Helicase
by: Bo Zhang, et al.
Published: (2022-01-01) -
Structural basis for DNA unwinding at forked dsDNA by two coordinating Pif1 helicases
by: Nannan Su, et al.
Published: (2019-11-01)