The active-zone protein Munc13 controls the use-dependence of presynaptic voltage-gated calcium channels

The active-zone protein Munc13 controls the use-dependence of presynaptic voltage-gated calcium channels

Presynaptic calcium channel function is critical for converting electrical information into chemical communication but the molecules in the active zone that sculpt this function are poorly understood. We show that Munc13, an active-zone protein essential for exocytosis, also controls presynaptic vol...

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Bibliographic Details
Main Authors: Nathaniel Calloway, Géraldine Gouzer, Mingyu Xue, Timothy A Ryan
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-07-01
Series:eLife
Subjects:
Munc13
calcium channel
plasticity
Online Access:https://elifesciences.org/articles/07728

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