The Cys Sense: Thiol Redox Switches Mediate Life Cycles of Cellular Proteins

The Cys Sense: Thiol Redox Switches Mediate Life Cycles of Cellular Proteins

Protein homeostasis is an essential component of proper cellular function; however, sustaining protein health is a challenging task, especially during the aerobic lifestyle. Natural cellular oxidants may be involved in cell signaling and antibacterial defense; however, imbalanced levels can lead to...

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Bibliographic Details
Main Authors: Meytal Radzinski, Tal Oppenheim, Norman Metanis, Dana Reichmann
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Biomolecules
Subjects:
thiol switches
proteostasis
chaperones
protein degradation
oxidative stress
redox-regulated proteins
Online Access:https://www.mdpi.com/2218-273X/11/3/469

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