Zebrafish models of the immune response: taking it on the ChIn

<p>Abstract</p> <p>The zebrafish is proving to be an extremely versatile new experimental model for unraveling the mysteries of innate immunity and has considerable promise as a system for the identification of novel modulators of this crucial biological process. A rate-limiting fa...

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Bibliographic Details
Main Authors: Ingham Philip W, Renshaw Stephen A
Format: Article
Language:English
Published: BMC 2010-12-01
Series:BMC Biology
Online Access:http://www.biomedcentral.com/1741-7007/8/148
Description
Summary:<p>Abstract</p> <p>The zebrafish is proving to be an extremely versatile new experimental model for unraveling the mysteries of innate immunity and has considerable promise as a system for the identification of novel modulators of this crucial biological process. A rate-limiting factor, however, is the mechanical stimulus required to induce the inflammatory response. A new chemically induced inflammation assay ('ChIn' assay) published in <it>BMC Biology </it>obviates this requirement and seems set to accelerate progress in the field.</p>
ISSN:1741-7007