Improved production of 2′-fucosyllactose in engineered Saccharomyces cerevisiae expressing a putative α-1, 2-fucosyltransferase from Bacillus cereus

Improved production of 2′-fucosyllactose in engineered Saccharomyces cerevisiae expressing a putative α-1, 2-fucosyltransferase from Bacillus cereus

Abstract Background 2′-fucosyllactose (2′-FL) is one of the most abundant oligosaccharides in human milk. It constitutes an authorized functional additive to improve infant nutrition and health in manufactured infant formulations. As a result, a cost-effective method for mass production of 2′-FL is...

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Bibliographic Details
Main Authors: Mingyuan Xu, Xiangfeng Meng, Weixin Zhang, Yu Shen, Weifeng Liu
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Microbial Cell Factories
Subjects:
2′-fucosyllactose
α-1, 2-fucosyltransferase
Bacillus cereus
Saccharomyces cerevisiae
GDP-l-fucose
Online Access:https://doi.org/10.1186/s12934-021-01657-5

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