Erectile dysfunction: Is platelet-rich plasma the new frontier for treatment in patients with erectile dysfunction? A review of the existing evidence
Erectile dysfunction (ED) is one of the commonest disorders in adult males and affects 12–19% of men of reproductive age. Only few studies have evaluated the impact of ED on men and couples with infertility—these studies report higher rates of ED in this sub-group of men compared to the general popu...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-08-01
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| Series: | Frontiers in Reproductive Health |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/frph.2022.944765/full |
| _version_ | 1798039857068507136 |
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| author | Eleni Anastasiadis Razna Ahmed Abbas Khizar Khoja Tet Yap Tet Yap |
| author_facet | Eleni Anastasiadis Razna Ahmed Abbas Khizar Khoja Tet Yap Tet Yap |
| author_sort | Eleni Anastasiadis |
| collection | DOAJ |
| description | Erectile dysfunction (ED) is one of the commonest disorders in adult males and affects 12–19% of men of reproductive age. Only few studies have evaluated the impact of ED on men and couples with infertility—these studies report higher rates of ED in this sub-group of men compared to the general population, with the prevalence of ED in men diagnosed with male infertility ranging from 6.7 to 61.6%. Nevertheless, ED is considered a rare cause of male infertility, accounting for about 0.4–5% of all causes of male infertility. ED remains a poorly treated condition globally and current therapies, like oral medication, offer only temporary symptomatic relief and do not influence disease progression—patients are potentially on lifelong treatment, with ED worsening over time. In contrast, regenerative medicine may potentially reverse or halt the progression of ED processes. In this article, we review the evidence for intracavernosal injections of platelet-rich plasma (PRP) in the treatment of ED. |
| first_indexed | 2024-04-11T21:59:28Z |
| format | Article |
| id | doaj.art-62b9742a65574cb690ec0ff250fdf14f |
| institution | Directory Open Access Journal |
| issn | 2673-3153 |
| language | English |
| last_indexed | 2024-04-11T21:59:28Z |
| publishDate | 2022-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Reproductive Health |
| spelling | doaj.art-62b9742a65574cb690ec0ff250fdf14f2022-12-22T04:01:00ZengFrontiers Media S.A.Frontiers in Reproductive Health2673-31532022-08-01410.3389/frph.2022.944765944765Erectile dysfunction: Is platelet-rich plasma the new frontier for treatment in patients with erectile dysfunction? A review of the existing evidenceEleni Anastasiadis0Razna Ahmed1Abbas Khizar Khoja2Tet Yap3Tet Yap4Department of Urology, Croydon University Hospital NHS Trust, London, United KingdomGuy's, King's and St Thomas' School of Medical Education, King's College London, London, United KingdomGuy's, King's and St Thomas' School of Medical Education, King's College London, London, United KingdomGuy's, King's and St Thomas' School of Medical Education, King's College London, London, United KingdomDepartment of Urology, Guy's and St Thomas' NHS Foundation Trust, London, United KingdomErectile dysfunction (ED) is one of the commonest disorders in adult males and affects 12–19% of men of reproductive age. Only few studies have evaluated the impact of ED on men and couples with infertility—these studies report higher rates of ED in this sub-group of men compared to the general population, with the prevalence of ED in men diagnosed with male infertility ranging from 6.7 to 61.6%. Nevertheless, ED is considered a rare cause of male infertility, accounting for about 0.4–5% of all causes of male infertility. ED remains a poorly treated condition globally and current therapies, like oral medication, offer only temporary symptomatic relief and do not influence disease progression—patients are potentially on lifelong treatment, with ED worsening over time. In contrast, regenerative medicine may potentially reverse or halt the progression of ED processes. In this article, we review the evidence for intracavernosal injections of platelet-rich plasma (PRP) in the treatment of ED.https://www.frontiersin.org/articles/10.3389/frph.2022.944765/fullplatelet-rich plasma (PRP)regenerative medicineerectile dysfunctionmale infertilitybiotechnology |
| spellingShingle | Eleni Anastasiadis Razna Ahmed Abbas Khizar Khoja Tet Yap Tet Yap Erectile dysfunction: Is platelet-rich plasma the new frontier for treatment in patients with erectile dysfunction? A review of the existing evidence Frontiers in Reproductive Health platelet-rich plasma (PRP) regenerative medicine erectile dysfunction male infertility biotechnology |
| title | Erectile dysfunction: Is platelet-rich plasma the new frontier for treatment in patients with erectile dysfunction? A review of the existing evidence |
| title_full | Erectile dysfunction: Is platelet-rich plasma the new frontier for treatment in patients with erectile dysfunction? A review of the existing evidence |
| title_fullStr | Erectile dysfunction: Is platelet-rich plasma the new frontier for treatment in patients with erectile dysfunction? A review of the existing evidence |
| title_full_unstemmed | Erectile dysfunction: Is platelet-rich plasma the new frontier for treatment in patients with erectile dysfunction? A review of the existing evidence |
| title_short | Erectile dysfunction: Is platelet-rich plasma the new frontier for treatment in patients with erectile dysfunction? A review of the existing evidence |
| title_sort | erectile dysfunction is platelet rich plasma the new frontier for treatment in patients with erectile dysfunction a review of the existing evidence |
| topic | platelet-rich plasma (PRP) regenerative medicine erectile dysfunction male infertility biotechnology |
| url | https://www.frontiersin.org/articles/10.3389/frph.2022.944765/full |
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