Comparison of efficacy of vaginal misoprostol versus a synthetic osmotic dilator (Dilapan-S) for cervical preparation before operative hysteroscopy: A randomized controlled study
Objectives: To compare the need for mechanical cervical dilatation following vaginal misoprostol or synthetic osmotic dilator (Dilapan-S) usage for cervical preparation before operative hysteroscopy. Materials and Methods: Fifty-five premenopausal women scheduled for operative hysteroscopic procedur...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Gynecology and Minimally Invasive Therapy |
| Subjects: | |
| Online Access: | http://www.e-gmit.com/article.asp?issn=2213-3070;year=2023;volume=12;issue=4;spage=225;epage=229;aulast=Nair |
| _version_ | 1797649430529179648 |
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| author | Aiswarya K Nair Murali Subbaiah Dilip Kumar Maurya |
| author_facet | Aiswarya K Nair Murali Subbaiah Dilip Kumar Maurya |
| author_sort | Aiswarya K Nair |
| collection | DOAJ |
| description | Objectives: To compare the need for mechanical cervical dilatation following vaginal misoprostol or synthetic osmotic dilator (Dilapan-S) usage for cervical preparation before operative hysteroscopy.
Materials and Methods: Fifty-five premenopausal women scheduled for operative hysteroscopic procedures with a 26 Fr resectoscope were included in this randomized, controlled clinical trial. After randomization, either 400 μg of vaginal misoprostol or intracervical synthetic osmotic dilator (Dilapan-S) was inserted 12 h before operative hysteroscopy. The need for additional mechanical cervical dilatation before insertion of the resectoscope was compared between the two groups. Initial cervical diameter before mechanical dilatation, intraoperative complications (cervical tears, creation of a false passage), and ease of dilatation were also compared between the two groups.
Results: In the misoprostol group, 92% of women required additional mechanical cervical dilatation, whereas only 36% of women in the Dilapan-S group required additional dilatation (P < 0.05). The median initial cervical diameter achieved with Dilapan was 9 mm (Q1: 7 mm; Q3: 10 mm), and with misoprostol, it was 6 mm (Q1: 4.5 mm; Q3: 8 mm) (P < 0.05). There was no significant difference in other outcome parameters between the two groups.
Conclusion: Synthetic osmotic dilator (Dilapan-S) is more efficacious than vaginal misoprostol at ripening the cervix before operative hysteroscopy. |
| first_indexed | 2024-03-11T15:46:01Z |
| format | Article |
| id | doaj.art-62b9e3b0298944f8a153fdba557e9e6d |
| institution | Directory Open Access Journal |
| issn | 2213-3070 |
| language | English |
| last_indexed | 2024-03-11T15:46:01Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Gynecology and Minimally Invasive Therapy |
| spelling | doaj.art-62b9e3b0298944f8a153fdba557e9e6d2023-10-26T06:27:50ZengWolters Kluwer Medknow PublicationsGynecology and Minimally Invasive Therapy2213-30702023-01-0112422522910.4103/gmit.gmit_111_22Comparison of efficacy of vaginal misoprostol versus a synthetic osmotic dilator (Dilapan-S) for cervical preparation before operative hysteroscopy: A randomized controlled studyAiswarya K NairMurali SubbaiahDilip Kumar MauryaObjectives: To compare the need for mechanical cervical dilatation following vaginal misoprostol or synthetic osmotic dilator (Dilapan-S) usage for cervical preparation before operative hysteroscopy. Materials and Methods: Fifty-five premenopausal women scheduled for operative hysteroscopic procedures with a 26 Fr resectoscope were included in this randomized, controlled clinical trial. After randomization, either 400 μg of vaginal misoprostol or intracervical synthetic osmotic dilator (Dilapan-S) was inserted 12 h before operative hysteroscopy. The need for additional mechanical cervical dilatation before insertion of the resectoscope was compared between the two groups. Initial cervical diameter before mechanical dilatation, intraoperative complications (cervical tears, creation of a false passage), and ease of dilatation were also compared between the two groups. Results: In the misoprostol group, 92% of women required additional mechanical cervical dilatation, whereas only 36% of women in the Dilapan-S group required additional dilatation (P < 0.05). The median initial cervical diameter achieved with Dilapan was 9 mm (Q1: 7 mm; Q3: 10 mm), and with misoprostol, it was 6 mm (Q1: 4.5 mm; Q3: 8 mm) (P < 0.05). There was no significant difference in other outcome parameters between the two groups. Conclusion: Synthetic osmotic dilator (Dilapan-S) is more efficacious than vaginal misoprostol at ripening the cervix before operative hysteroscopy.http://www.e-gmit.com/article.asp?issn=2213-3070;year=2023;volume=12;issue=4;spage=225;epage=229;aulast=Naircervical ripeningdilapan-smisoprostoloperative hysteroscopyresectoscope |
| spellingShingle | Aiswarya K Nair Murali Subbaiah Dilip Kumar Maurya Comparison of efficacy of vaginal misoprostol versus a synthetic osmotic dilator (Dilapan-S) for cervical preparation before operative hysteroscopy: A randomized controlled study Gynecology and Minimally Invasive Therapy cervical ripening dilapan-s misoprostol operative hysteroscopy resectoscope |
| title | Comparison of efficacy of vaginal misoprostol versus a synthetic osmotic dilator (Dilapan-S) for cervical preparation before operative hysteroscopy: A randomized controlled study |
| title_full | Comparison of efficacy of vaginal misoprostol versus a synthetic osmotic dilator (Dilapan-S) for cervical preparation before operative hysteroscopy: A randomized controlled study |
| title_fullStr | Comparison of efficacy of vaginal misoprostol versus a synthetic osmotic dilator (Dilapan-S) for cervical preparation before operative hysteroscopy: A randomized controlled study |
| title_full_unstemmed | Comparison of efficacy of vaginal misoprostol versus a synthetic osmotic dilator (Dilapan-S) for cervical preparation before operative hysteroscopy: A randomized controlled study |
| title_short | Comparison of efficacy of vaginal misoprostol versus a synthetic osmotic dilator (Dilapan-S) for cervical preparation before operative hysteroscopy: A randomized controlled study |
| title_sort | comparison of efficacy of vaginal misoprostol versus a synthetic osmotic dilator dilapan s for cervical preparation before operative hysteroscopy a randomized controlled study |
| topic | cervical ripening dilapan-s misoprostol operative hysteroscopy resectoscope |
| url | http://www.e-gmit.com/article.asp?issn=2213-3070;year=2023;volume=12;issue=4;spage=225;epage=229;aulast=Nair |
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