A novel approach for direct detection of the IGH::CRLF2 gene fusion by fluorescent in situ hybridization

A novel approach for direct detection of the IGH::CRLF2 gene fusion by fluorescent in situ hybridization

Abstract Background High expression of the Cytokine Receptor-Like Factor 2 (CRLF2) gene has been observed in patients with acute lymphoblastic leukemia BCR-ABL1-like subtype. Currently, there is no commercial system available for the direct detection of the IGH::CRLF2 fusion by fluorescent in situ h...

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Bibliographic Details
Main Authors:	Rosa María González-Arreola, Adriana García-Romero, María Teresa Magaña-Torres, Juan Ramón González-García
Format:	Article
Language:	English
Published:	BMC 2023-08-01
Series:	Molecular Cytogenetics
Subjects:	Acute lymphoblastic leukemia IGH::CRLF2 gene fusion BCR-ABL1-like Fluorescent in situ hybridization Break-apart probes Gene fusions
Online Access:	https://doi.org/10.1186/s13039-023-00652-2

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