Neuroprotective Effects of Sodium Butyrate by Restoring Gut Microbiota and Inhibiting TLR4 Signaling in Mice with MPTP-Induced Parkinson’s Disease

Neuroprotective Effects of Sodium Butyrate by Restoring Gut Microbiota and Inhibiting TLR4 Signaling in Mice with MPTP-Induced Parkinson’s Disease

Parkinson’s disease (PD) is a prevalent type of neurodegenerative disease. There is mounting evidence that the gut microbiota is involved in the pathogenesis of PD. Sodium butyrate (NaB) can regulate gut microbiota and improve brain functioning in neurological disorders. Hence, we examined whether t...

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Bibliographic Details
Main Authors: Tong-Tong Guo, Zheng Zhang, Yan Sun, Rui-Yang Zhu, Fei-Xia Wang, Lian-Ju Ma, Lin Jiang, Han-Deng Liu
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Nutrients
Subjects:
sodium butyrate
microbiome–gut–brain axis
neuroinflammation
gut microbial dysbiosis
Parkinson’s disease
Online Access:https://www.mdpi.com/2072-6643/15/4/930

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