A population-based cohort of adults with asthma: mortality and participation in a long-term follow-up
Background and objective: Asthma is a major public health concern. The aim of this study was to characterize a large population-based cohort of adults with asthma, and to study factors associated with all-cause mortality and non-participation in a long-term follow-up. Design: Random and stratified s...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2017-01-01
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| Series: | European Clinical Respiratory Journal |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/20018525.2017.1334508 |
| _version_ | 1831540719537356800 |
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| author | Helena Backman Linnea Hedman Caroline Stridsman Sven-Arne Jansson Anne Lindberg Bo Lundbäck Eva Rönmark |
| author_facet | Helena Backman Linnea Hedman Caroline Stridsman Sven-Arne Jansson Anne Lindberg Bo Lundbäck Eva Rönmark |
| author_sort | Helena Backman |
| collection | DOAJ |
| description | Background and objective: Asthma is a major public health concern. The aim of this study was to characterize a large population-based cohort of adults with asthma, and to study factors associated with all-cause mortality and non-participation in a long-term follow-up. Design: Random and stratified samples from five population-based cohorts were clinically examined during 1986–2001, and all subjects with asthma were included in the study (n = 2055, age 19–72 years, 55% women). Independent associations between different risk factors and (i) mortality and (ii) non-participation in a clinical follow-up in 2012–2014 were estimated. Results: In 1986–2001, 95% reported any wheeze and/or attacks of shortness of breath in the past 12 months, and/or asthma medication use. Over the up to 28 years of follow-up time, the cumulative mortality was 22.7%. Male gender, current smoking, and lower forced expiratory volume in 1 sec of predicted (FEV1% of predicted) were independent risk factors for mortality, while obesity was associated with non-participation in the follow-up. Older ages, ischemic heart disease, and low socioeconomic status were associated with both mortality and non-participation. Conclusions: The risk factors associated with mortality in this adult population-based asthma cohort were similar to those commonly identified in general population samples, i.e. male gender, current smoking, and lower FEV1% of predicted, while obesity was associated with non-participation in a long-term follow-up. Ischemic heart disease, low socioeconomic status, and older ages were associated with both mortality and non-participation. |
| first_indexed | 2024-12-17T00:04:09Z |
| format | Article |
| id | doaj.art-62cbf09cd5514804a197f27ca2b67074 |
| institution | Directory Open Access Journal |
| issn | 2001-8525 |
| language | English |
| last_indexed | 2024-12-17T00:04:09Z |
| publishDate | 2017-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | European Clinical Respiratory Journal |
| spelling | doaj.art-62cbf09cd5514804a197f27ca2b670742022-12-21T22:11:00ZengTaylor & Francis GroupEuropean Clinical Respiratory Journal2001-85252017-01-014110.1080/20018525.2017.13345081334508A population-based cohort of adults with asthma: mortality and participation in a long-term follow-upHelena Backman0Linnea Hedman1Caroline Stridsman2Sven-Arne Jansson3Anne Lindberg4Bo Lundbäck5Eva Rönmark6Umeå UniversityUmeå UniversityLuleå UniversityUmeå UniversityUmeå UniversityUniversity of GothenburgUmeå UniversityBackground and objective: Asthma is a major public health concern. The aim of this study was to characterize a large population-based cohort of adults with asthma, and to study factors associated with all-cause mortality and non-participation in a long-term follow-up. Design: Random and stratified samples from five population-based cohorts were clinically examined during 1986–2001, and all subjects with asthma were included in the study (n = 2055, age 19–72 years, 55% women). Independent associations between different risk factors and (i) mortality and (ii) non-participation in a clinical follow-up in 2012–2014 were estimated. Results: In 1986–2001, 95% reported any wheeze and/or attacks of shortness of breath in the past 12 months, and/or asthma medication use. Over the up to 28 years of follow-up time, the cumulative mortality was 22.7%. Male gender, current smoking, and lower forced expiratory volume in 1 sec of predicted (FEV1% of predicted) were independent risk factors for mortality, while obesity was associated with non-participation in the follow-up. Older ages, ischemic heart disease, and low socioeconomic status were associated with both mortality and non-participation. Conclusions: The risk factors associated with mortality in this adult population-based asthma cohort were similar to those commonly identified in general population samples, i.e. male gender, current smoking, and lower FEV1% of predicted, while obesity was associated with non-participation in a long-term follow-up. Ischemic heart disease, low socioeconomic status, and older ages were associated with both mortality and non-participation.http://dx.doi.org/10.1080/20018525.2017.1334508public healthrisk factorsnatural historyobesityischemic heart diseasesocioeconomic status |
| spellingShingle | Helena Backman Linnea Hedman Caroline Stridsman Sven-Arne Jansson Anne Lindberg Bo Lundbäck Eva Rönmark A population-based cohort of adults with asthma: mortality and participation in a long-term follow-up European Clinical Respiratory Journal public health risk factors natural history obesity ischemic heart disease socioeconomic status |
| title | A population-based cohort of adults with asthma: mortality and participation in a long-term follow-up |
| title_full | A population-based cohort of adults with asthma: mortality and participation in a long-term follow-up |
| title_fullStr | A population-based cohort of adults with asthma: mortality and participation in a long-term follow-up |
| title_full_unstemmed | A population-based cohort of adults with asthma: mortality and participation in a long-term follow-up |
| title_short | A population-based cohort of adults with asthma: mortality and participation in a long-term follow-up |
| title_sort | population based cohort of adults with asthma mortality and participation in a long term follow up |
| topic | public health risk factors natural history obesity ischemic heart disease socioeconomic status |
| url | http://dx.doi.org/10.1080/20018525.2017.1334508 |
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