Antiviral Strategies for Pandemic and Seasonal Influenza
While vaccines are the primary public health response to seasonal and pandemic flu, short of a universal vaccine there are inherent limitations to this approach. Antiviral drugs provide valuable alternative options for treatment and prophylaxis of influenza. Here, we will review drugs and drug candi...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2010-08-01
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| Series: | Viruses |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1999-4915/2/8/1766/ |
| _version_ | 1819041036701270016 |
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| author | Fang Fang Maria Hedlund Jeffrey L. Larson |
| author_facet | Fang Fang Maria Hedlund Jeffrey L. Larson |
| author_sort | Fang Fang |
| collection | DOAJ |
| description | While vaccines are the primary public health response to seasonal and pandemic flu, short of a universal vaccine there are inherent limitations to this approach. Antiviral drugs provide valuable alternative options for treatment and prophylaxis of influenza. Here, we will review drugs and drug candidates against influenza with an emphasis on the recent progress of a host-targeting entry-blocker drug candidate, DAS181, a sialidase fusion protein. |
| first_indexed | 2024-12-21T09:18:37Z |
| format | Article |
| id | doaj.art-62cc3dfae3ff4645b9591959408629f6 |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-12-21T09:18:37Z |
| publishDate | 2010-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-62cc3dfae3ff4645b9591959408629f62022-12-21T19:09:05ZengMDPI AGViruses1999-49152010-08-01281766178110.3390/v2081766Antiviral Strategies for Pandemic and Seasonal InfluenzaFang FangMaria HedlundJeffrey L. LarsonWhile vaccines are the primary public health response to seasonal and pandemic flu, short of a universal vaccine there are inherent limitations to this approach. Antiviral drugs provide valuable alternative options for treatment and prophylaxis of influenza. Here, we will review drugs and drug candidates against influenza with an emphasis on the recent progress of a host-targeting entry-blocker drug candidate, DAS181, a sialidase fusion protein.http://www.mdpi.com/1999-4915/2/8/1766/influenza virusneuraminidase inhibitorssialic acidRNA polymerase |
| spellingShingle | Fang Fang Maria Hedlund Jeffrey L. Larson Antiviral Strategies for Pandemic and Seasonal Influenza Viruses influenza virus neuraminidase inhibitors sialic acid RNA polymerase |
| title | Antiviral Strategies for Pandemic and Seasonal Influenza |
| title_full | Antiviral Strategies for Pandemic and Seasonal Influenza |
| title_fullStr | Antiviral Strategies for Pandemic and Seasonal Influenza |
| title_full_unstemmed | Antiviral Strategies for Pandemic and Seasonal Influenza |
| title_short | Antiviral Strategies for Pandemic and Seasonal Influenza |
| title_sort | antiviral strategies for pandemic and seasonal influenza |
| topic | influenza virus neuraminidase inhibitors sialic acid RNA polymerase |
| url | http://www.mdpi.com/1999-4915/2/8/1766/ |
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