Cervical squamous and glandular intraepithelial neoplasia: identification and current management approaches
Certain types of human papillomaviruses (HPV) are associated with squamous intraepithelial lesions and cancer and these are termed high-risk. HPV type 16 is detected in approximately half of the high-grade squamous intraepithelial lesions and cancer. Because of the high rate of spontaneous regressio...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Instituto Nacional de Salud Pública
2003-01-01
|
| Series: | Salud Pública de México |
| Subjects: | |
| Online Access: | http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0036-36342003000900016 |
| _version_ | 1818546162532089856 |
|---|---|
| author | Wright V Cecil |
| author_facet | Wright V Cecil |
| author_sort | Wright V Cecil |
| collection | DOAJ |
| description | Certain types of human papillomaviruses (HPV) are associated with squamous intraepithelial lesions and cancer and these are termed high-risk. HPV type 16 is detected in approximately half of the high-grade squamous intraepithelial lesions and cancer. Because of the high rate of spontaneous regression of low-grade squamous lesions, follow-up by cytology, colposcopy and possible biopsy appears preferable. Due to the higher rate of progression to malignancy of the high-grade lesions conservative treatment is recommended. One of the most common reasons for persistence relates to the human immunodeficiency virus. Adenocarcinoma in situ is an uncommon disorder and not well identified by cytologic sampling or colposcopic inspection. The diagnosis is made by cone biopsy, the specimen having negative margins for disease. Hysterectomy is the treatment procedure of choice unless fertility is an issue. Excisional methods (particularly electrosurgical loop) can interfere with accurate histological interpretation in some cases of both squamous disease and adenocarcinoma in situ. |
| first_indexed | 2024-12-12T07:49:31Z |
| format | Article |
| id | doaj.art-62cc4bcef9fb419186ad2ab2b0071dd7 |
| institution | Directory Open Access Journal |
| issn | 0036-3634 |
| language | English |
| last_indexed | 2024-12-12T07:49:31Z |
| publishDate | 2003-01-01 |
| publisher | Instituto Nacional de Salud Pública |
| record_format | Article |
| series | Salud Pública de México |
| spelling | doaj.art-62cc4bcef9fb419186ad2ab2b0071dd72022-12-22T00:32:29ZengInstituto Nacional de Salud PúblicaSalud Pública de México0036-36342003-01-0145suppl.3417429Cervical squamous and glandular intraepithelial neoplasia: identification and current management approachesWright V CecilCertain types of human papillomaviruses (HPV) are associated with squamous intraepithelial lesions and cancer and these are termed high-risk. HPV type 16 is detected in approximately half of the high-grade squamous intraepithelial lesions and cancer. Because of the high rate of spontaneous regression of low-grade squamous lesions, follow-up by cytology, colposcopy and possible biopsy appears preferable. Due to the higher rate of progression to malignancy of the high-grade lesions conservative treatment is recommended. One of the most common reasons for persistence relates to the human immunodeficiency virus. Adenocarcinoma in situ is an uncommon disorder and not well identified by cytologic sampling or colposcopic inspection. The diagnosis is made by cone biopsy, the specimen having negative margins for disease. Hysterectomy is the treatment procedure of choice unless fertility is an issue. Excisional methods (particularly electrosurgical loop) can interfere with accurate histological interpretation in some cases of both squamous disease and adenocarcinoma in situ.http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0036-36342003000900016squamous intraepithelial neoplasiaadenocarcinoma in situconservative treatment |
| spellingShingle | Wright V Cecil Cervical squamous and glandular intraepithelial neoplasia: identification and current management approaches Salud Pública de México squamous intraepithelial neoplasia adenocarcinoma in situ conservative treatment |
| title | Cervical squamous and glandular intraepithelial neoplasia: identification and current management approaches |
| title_full | Cervical squamous and glandular intraepithelial neoplasia: identification and current management approaches |
| title_fullStr | Cervical squamous and glandular intraepithelial neoplasia: identification and current management approaches |
| title_full_unstemmed | Cervical squamous and glandular intraepithelial neoplasia: identification and current management approaches |
| title_short | Cervical squamous and glandular intraepithelial neoplasia: identification and current management approaches |
| title_sort | cervical squamous and glandular intraepithelial neoplasia identification and current management approaches |
| topic | squamous intraepithelial neoplasia adenocarcinoma in situ conservative treatment |
| url | http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0036-36342003000900016 |
| work_keys_str_mv | AT wrightvcecil cervicalsquamousandglandularintraepithelialneoplasiaidentificationandcurrentmanagementapproaches |