Engineering an enthesis-like graft for rotator cuff repair: An approach to fabricate highly biomimetic scaffold capable of zone-specifically releasing stem cell differentiation inducers

Engineering an enthesis-like graft for rotator cuff repair: An approach to fabricate highly biomimetic scaffold capable of zone-specifically releasing stem cell differentiation inducers

Rotator cuff (RC) attaches to humerus across a triphasic yet continuous tissue zones (bone-fibrocartilage-tendon), termed “enthesis”. Regrettably, rapid and functional enthesis regeneration is challenging after RC tear. The existing grafts bioengineered for RC repair are insufficient, as they were e...

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Bibliographic Details
Main Authors: Can Chen, Qiang Shi, Muzhi Li, Yang Chen, Tao Zhang, Yan Xu, Yunjie Liao, Shulin Ding, Zhanwen Wang, Xing Li, Chunfeng Zhao, Lunquan Sun, Jianzhong Hu, Hongbin Lu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-10-01
Series:Bioactive Materials
Subjects:
Acellular matrix
Collagen-binding peptide
Stem cell differentiation inducer
Enthesis regeneration
Rotator cuff
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X21005958

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http://www.sciencedirect.com/science/article/pii/S2452199X21005958

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