Transmitted virus fitness and host T cell responses collectively define divergent infection outcomes in two HIV-1 recipients.

Transmitted virus fitness and host T cell responses collectively define divergent infection outcomes in two HIV-1 recipients.

Control of virus replication in HIV-1 infection is critical to delaying disease progression. While cellular immune responses are a key determinant of control, relatively little is known about the contribution of the infecting virus to this process. To gain insight into this interplay between virus a...

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Bibliographic Details
Main Authors: Ling Yue, Katja J Pfafferott, Joshua Baalwa, Karen Conrod, Catherine C Dong, Cecilia Chui, Rong Rong, Daniel T Claiborne, Jessica L Prince, Jianming Tang, Ruy M Ribeiro, Emmanuel Cormier, Beatrice H Hahn, Alan S Perelson, George M Shaw, Etienne Karita, Jill Gilmour, Paul Goepfert, Cynthia A Derdeyn, Susan A Allen, Persephone Borrow, Eric Hunter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1004565

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