Anal squamous cell carcinoma: Impact of radiochemotherapy evolution over years and an explorative analysis of MRI prediction of tumor response in a mono-institutional series of 131 patients

Anal squamous cell carcinoma: Impact of radiochemotherapy evolution over years and an explorative analysis of MRI prediction of tumor response in a mono-institutional series of 131 patients

IntroductionRadiochemotherapy (RCHT) for the treatment of anal squamous cell carcinoma (ASCC) has evolved dramatically, also thanks to intensity-modulated RT (IMRT) and 3D image guidance (3D IGRT). Despite most patients presenting fair outcomes, unmet needs still exist. Predictors of poor tumor resp...

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Bibliographic Details
Main Authors: Marco Lorenzo Bonù, Salvatore La Mattina, Navdeep Singh, Cristian Toraci, Luigi Spiazzi, Fabrizia Terraneo, Fernando Barbera, Paola Vitali, Francesco Frassine, Andrea Guerini, Luca Triggiani, Davide Tomasini, Vittorio Morelli, Jessica Imbrescia, Jacopo Andreuccetti, Barbara Frittoli, Frida Pittiani, Luigi Grazioli, Nazario Portolani, Luca Nicosia, Domenico Albano, Francesco Bertagna, Stefano Maria Magrini, Michela Buglione
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Oncology
Subjects:
anal cancer (AC)
radiotherapy–chemotherapy
IMRT (intensity modulated radiation therapy)
predictive modeling
mri
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.973223/full

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