Investigation of the chromosome regions with significant affinity for the nuclear envelope in fruit fly--a model based approach.
Three dimensional nuclear architecture is important for genome function, but is still poorly understood. In particular, little is known about the role of the "boundary conditions"--points of attachment between chromosomes and the nuclear envelope. We describe a method for modeling the 3D o...
Main Authors: | Nicholas Allen Kinney, Igor V Sharakhov, Alexey V Onufriev |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3961273?pdf=render |
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