Streptococcus suis subtilisin-like serine proteases SspA-1 and SspA-2 interplay with complement C3a and C5a to facilitate bacterial immune evasion and infection

Streptococcus suis subtilisin-like serine proteases SspA-1 and SspA-2 interplay with complement C3a and C5a to facilitate bacterial immune evasion and infection

ABSTRACTStreptococcus suis (S. suis), a significant zoonotic bacterial pathogen impacting swine and human, is associated with severe systemic diseases such as streptococcal toxic shock-like syndrome, meningitis, septicaemia, and abrupt fatality. The multifaceted roles of complement components C5a an...

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Bibliographic Details
Main Authors: Simin Deng, Junhui Liao, Haojie Li, Jiali Xu, Jingyan Fan, Jing Xia, Jing Wang, Lei Lei, Mianmian Chen, Yue Han, Ruidong Zhai, Chang Zhou, Rui Zhou, Changyong Cheng, Houhui Song
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Virulence
Subjects:
Streptococcus suis
complement evasion
subtilisin-like serine proteases
C3a and C5a
monocyte chemotaxis
pathogenicity
Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2023.2301246

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