Losartan protects human stem cell-derived cardiomyocytes from angiotensin II-induced alcoholic cardiotoxicity

Losartan protects human stem cell-derived cardiomyocytes from angiotensin II-induced alcoholic cardiotoxicity

Abstract Alcoholic cardiomyopathy (ACM) is a myocardial injury caused by long-term heavy drinking. Existing evidence indicates that high levels of oxidative stress are the key to pathological cardiomyopathy caused by long-term exposure to high concentrations of alcohol, while angiotensin II (AngII)...

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Bibliographic Details
Main Authors: Yuanxiu Song, Hongxia Li, Shuhong Ma, Min Zhu, Wen-jing Lu, Feng Lan, Ming Cui
Format: Article
Language:English
Published: Nature Publishing Group 2022-03-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-00945-2

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