Pentoxifylline Inhibits TNF-α/TGF-β1-Induced Epithelial-Mesenchymal Transition via Suppressing the NF-κB Pathway and <i>SERPINE1</i> Expression in CaSki Cells

Pentoxifylline Inhibits TNF-α/TGF-β1-Induced Epithelial-Mesenchymal Transition via Suppressing the NF-κB Pathway and <i>SERPINE1</i> Expression in CaSki Cells

Cervical cancer (CC) is one of the most common and deadly types of female cancer worldwide. Late diagnosis in CC increases the risk of tumor cells spreading to distant organs (metastasis). The epithelial-mesenchymal transition (EMT) is a fundamental process of cancer metastasis. Inflammation can lea...

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Bibliographic Details
Main Authors: Luis Arturo Palafox-Mariscal, Pablo Cesar Ortiz-Lazareno, Luis Felipe Jave-Suárez, Adriana Aguilar-Lemarroy, María Martha Villaseñor-García, José Roberto Cruz-Lozano, Karen Lilith González-Martínez, Aníbal Samael Méndez-Clemente, Alejandro Bravo-Cuellar, Georgina Hernández-Flores
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
pentoxifylline
epithelial-mesenchymal transition
NF-κB
<i>SERPINE1</i>
CaSki cells
Online Access:https://www.mdpi.com/1422-0067/24/13/10592

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