EXPERIENCE OF TREATMENT WITH ABATACEPT IN PATIENTS WITH JUVENILE RHEUMATOID ARTHRITIS
The article presents a case report of a patient with juvenile rheumatoid arthritis refractory to the treatment with metothrexate. Combined therapy with metothrexate and leflunomide induced development of unfavorable effects resulted in cancellation of leflunomide. Successful administration of biolog...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
"Paediatrician" Publishers LLC
2011-01-01
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| Series: | Вопросы современной педиатрии |
| Subjects: | |
| Online Access: | https://vsp.spr-journal.ru/jour/article/view/557 |
| _version_ | 1797697541280628736 |
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| author | Ye. I. Alekseyeva S. I. Valiyeva T. V. Sleptsova |
| author_facet | Ye. I. Alekseyeva S. I. Valiyeva T. V. Sleptsova |
| author_sort | Ye. I. Alekseyeva |
| collection | DOAJ |
| description | The article presents a case report of a patient with juvenile rheumatoid arthritis refractory to the treatment with metothrexate. Combined therapy with metothrexate and leflunomide induced development of unfavorable effects resulted in cancellation of leflunomide. Successful administration of biological agent inhibitor of T-lymphocytes co-stimulation abatacept is described. Treatment with abatacept resulted in remission of a disease; it increased patient and her family’s quality of life. |
| first_indexed | 2024-03-12T03:41:40Z |
| format | Article |
| id | doaj.art-62ea1066a31b49eeb882f0e5d4db571e |
| institution | Directory Open Access Journal |
| issn | 1682-5527 1682-5535 |
| language | English |
| last_indexed | 2024-03-12T03:41:40Z |
| publishDate | 2011-01-01 |
| publisher | "Paediatrician" Publishers LLC |
| record_format | Article |
| series | Вопросы современной педиатрии |
| spelling | doaj.art-62ea1066a31b49eeb882f0e5d4db571e2023-09-03T13:02:28Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352011-01-01101160166557EXPERIENCE OF TREATMENT WITH ABATACEPT IN PATIENTS WITH JUVENILE RHEUMATOID ARTHRITISYe. I. Alekseyeva0S. I. Valiyeva1T. V. Sleptsova2Научный центр здоровья детей РАМН, Москва; Первый Московский государственный медицинский университет им. И.М. СеченоваНаучный центр здоровья детей РАМН, МоскваНаучный центр здоровья детей РАМН, МоскваThe article presents a case report of a patient with juvenile rheumatoid arthritis refractory to the treatment with metothrexate. Combined therapy with metothrexate and leflunomide induced development of unfavorable effects resulted in cancellation of leflunomide. Successful administration of biological agent inhibitor of T-lymphocytes co-stimulation abatacept is described. Treatment with abatacept resulted in remission of a disease; it increased patient and her family’s quality of life.https://vsp.spr-journal.ru/jour/article/view/557детиювенильный ревматоидный артритабатацептлечение |
| spellingShingle | Ye. I. Alekseyeva S. I. Valiyeva T. V. Sleptsova EXPERIENCE OF TREATMENT WITH ABATACEPT IN PATIENTS WITH JUVENILE RHEUMATOID ARTHRITIS Вопросы современной педиатрии дети ювенильный ревматоидный артрит абатацепт лечение |
| title | EXPERIENCE OF TREATMENT WITH ABATACEPT IN PATIENTS WITH JUVENILE RHEUMATOID ARTHRITIS |
| title_full | EXPERIENCE OF TREATMENT WITH ABATACEPT IN PATIENTS WITH JUVENILE RHEUMATOID ARTHRITIS |
| title_fullStr | EXPERIENCE OF TREATMENT WITH ABATACEPT IN PATIENTS WITH JUVENILE RHEUMATOID ARTHRITIS |
| title_full_unstemmed | EXPERIENCE OF TREATMENT WITH ABATACEPT IN PATIENTS WITH JUVENILE RHEUMATOID ARTHRITIS |
| title_short | EXPERIENCE OF TREATMENT WITH ABATACEPT IN PATIENTS WITH JUVENILE RHEUMATOID ARTHRITIS |
| title_sort | experience of treatment with abatacept in patients with juvenile rheumatoid arthritis |
| topic | дети ювенильный ревматоидный артрит абатацепт лечение |
| url | https://vsp.spr-journal.ru/jour/article/view/557 |
| work_keys_str_mv | AT yeialekseyeva experienceoftreatmentwithabataceptinpatientswithjuvenilerheumatoidarthritis AT sivaliyeva experienceoftreatmentwithabataceptinpatientswithjuvenilerheumatoidarthritis AT tvsleptsova experienceoftreatmentwithabataceptinpatientswithjuvenilerheumatoidarthritis |