Coronary Artery Occlusion with Sharp Blood Pressure Drop during General Anesthesia Induction: A Case Report

Most anesthetics reduce cardiac functions and lower blood pressure (BP), potentially causing excessive BP reduction in dehydrated patients or those with heart conditions, such as coronary artery disease (CAD). Considering the increased prevalence of cardiovascular disease with age, anesthesiologists...

Full description

Bibliographic Details
Main Authors: Jae Young Ji, Yong Han Seo, Ho Soon Jung, Hea Rim Chun, Jin Soo Park, Woo Jong Kim, Jae Min Ahn, Yu Jun Park, Ye Eun Shin, Chan Ho Park
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1648-9144/60/2/232
_version_ 1797297541002297344
author Jae Young Ji
Yong Han Seo
Ho Soon Jung
Hea Rim Chun
Jin Soo Park
Woo Jong Kim
Jae Min Ahn
Yu Jun Park
Ye Eun Shin
Chan Ho Park
author_facet Jae Young Ji
Yong Han Seo
Ho Soon Jung
Hea Rim Chun
Jin Soo Park
Woo Jong Kim
Jae Min Ahn
Yu Jun Park
Ye Eun Shin
Chan Ho Park
author_sort Jae Young Ji
collection DOAJ
description Most anesthetics reduce cardiac functions and lower blood pressure (BP), potentially causing excessive BP reduction in dehydrated patients or those with heart conditions, such as coronary artery disease (CAD). Considering the increased prevalence of cardiovascular disease with age, anesthesiologists must be cautious about BP reduction during general anesthesia in older adults. In the present case, a 76-year-old male patient with undiagnosed CAD in a hypovolemic state experienced a significant drop in systolic BP to the fifties during propofol and sevoflurane anesthesia. Despite the use of vasopressors, excessive hypotension persisted, leading to anesthesia suspension. Subsequent cardiac examinations, including computed tomography heart angio and calcium score, and coronary angiogram, revealed a near total occlusion of the proximal left anterior descending coronary artery (pLAD) and the formation of collateral circulation. After 5 days of hydration and anticoagulation medications and confirmation of normovolemic state, general anesthesia was attempted again and successfully induced; a normal BP was maintained throughout the surgery. Thus, it is important to conduct a thorough cardiac evaluation and maintain normovolemia for general anesthesia in older adults.
first_indexed 2024-03-07T22:22:49Z
format Article
id doaj.art-62eb4c525d654818994191d62e49d855
institution Directory Open Access Journal
issn 1010-660X
1648-9144
language English
last_indexed 2024-03-07T22:22:49Z
publishDate 2024-01-01
publisher MDPI AG
record_format Article
series Medicina
spelling doaj.art-62eb4c525d654818994191d62e49d8552024-02-23T15:26:30ZengMDPI AGMedicina1010-660X1648-91442024-01-0160223210.3390/medicina60020232Coronary Artery Occlusion with Sharp Blood Pressure Drop during General Anesthesia Induction: A Case ReportJae Young Ji0Yong Han Seo1Ho Soon Jung2Hea Rim Chun3Jin Soo Park4Woo Jong Kim5Jae Min Ahn6Yu Jun Park7Ye Eun Shin8Chan Ho Park9Department of Anesthesiology and Pain Medicine, Soonchunhyang University Hospital Cheonan, 31, Suncheonhyang 6-gil, Dongam-gu, Cheonan 31151, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, Soonchunhyang University Hospital Cheonan, 31, Suncheonhyang 6-gil, Dongam-gu, Cheonan 31151, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, Soonchunhyang University Hospital Cheonan, 31, Suncheonhyang 6-gil, Dongam-gu, Cheonan 31151, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, Soonchunhyang University Hospital Cheonan, 31, Suncheonhyang 6-gil, Dongam-gu, Cheonan 31151, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, Soonchunhyang University Hospital Cheonan, 31, Suncheonhyang 6-gil, Dongam-gu, Cheonan 31151, Republic of KoreaDepartment of Orthopaedic Surgery, Soonchunhyang University Hospital Cheonan, 31, Suncheonhyang 6-gil, Dongam-gu, Cheonan 31151, Republic of KoreaDepartment of Neurosurgery, Soonchunhyang University Hospital Cheonan, 31, Suncheonhyang 6-gil, Dongam-gu, Cheonan 31151, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, Soonchunhyang University Hospital Cheonan, 31, Suncheonhyang 6-gil, Dongam-gu, Cheonan 31151, Republic of KoreaDepartment of Anesthesiology and Pain Medicine, Soonchunhyang University Hospital Cheonan, 31, Suncheonhyang 6-gil, Dongam-gu, Cheonan 31151, Republic of KoreaDepartment of Radiology, Soonchunhyang University Hospital Cheonan, 31, Sooncheonhyang 6-gil, Donam-gu, Cheonan 31151, Republic of KoreaMost anesthetics reduce cardiac functions and lower blood pressure (BP), potentially causing excessive BP reduction in dehydrated patients or those with heart conditions, such as coronary artery disease (CAD). Considering the increased prevalence of cardiovascular disease with age, anesthesiologists must be cautious about BP reduction during general anesthesia in older adults. In the present case, a 76-year-old male patient with undiagnosed CAD in a hypovolemic state experienced a significant drop in systolic BP to the fifties during propofol and sevoflurane anesthesia. Despite the use of vasopressors, excessive hypotension persisted, leading to anesthesia suspension. Subsequent cardiac examinations, including computed tomography heart angio and calcium score, and coronary angiogram, revealed a near total occlusion of the proximal left anterior descending coronary artery (pLAD) and the formation of collateral circulation. After 5 days of hydration and anticoagulation medications and confirmation of normovolemic state, general anesthesia was attempted again and successfully induced; a normal BP was maintained throughout the surgery. Thus, it is important to conduct a thorough cardiac evaluation and maintain normovolemia for general anesthesia in older adults.https://www.mdpi.com/1648-9144/60/2/232coronary artery diseasedehydrationpropofolsevoflurane
spellingShingle Jae Young Ji
Yong Han Seo
Ho Soon Jung
Hea Rim Chun
Jin Soo Park
Woo Jong Kim
Jae Min Ahn
Yu Jun Park
Ye Eun Shin
Chan Ho Park
Coronary Artery Occlusion with Sharp Blood Pressure Drop during General Anesthesia Induction: A Case Report
Medicina
coronary artery disease
dehydration
propofol
sevoflurane
title Coronary Artery Occlusion with Sharp Blood Pressure Drop during General Anesthesia Induction: A Case Report
title_full Coronary Artery Occlusion with Sharp Blood Pressure Drop during General Anesthesia Induction: A Case Report
title_fullStr Coronary Artery Occlusion with Sharp Blood Pressure Drop during General Anesthesia Induction: A Case Report
title_full_unstemmed Coronary Artery Occlusion with Sharp Blood Pressure Drop during General Anesthesia Induction: A Case Report
title_short Coronary Artery Occlusion with Sharp Blood Pressure Drop during General Anesthesia Induction: A Case Report
title_sort coronary artery occlusion with sharp blood pressure drop during general anesthesia induction a case report
topic coronary artery disease
dehydration
propofol
sevoflurane
url https://www.mdpi.com/1648-9144/60/2/232
work_keys_str_mv AT jaeyoungji coronaryarteryocclusionwithsharpbloodpressuredropduringgeneralanesthesiainductionacasereport
AT yonghanseo coronaryarteryocclusionwithsharpbloodpressuredropduringgeneralanesthesiainductionacasereport
AT hosoonjung coronaryarteryocclusionwithsharpbloodpressuredropduringgeneralanesthesiainductionacasereport
AT hearimchun coronaryarteryocclusionwithsharpbloodpressuredropduringgeneralanesthesiainductionacasereport
AT jinsoopark coronaryarteryocclusionwithsharpbloodpressuredropduringgeneralanesthesiainductionacasereport
AT woojongkim coronaryarteryocclusionwithsharpbloodpressuredropduringgeneralanesthesiainductionacasereport
AT jaeminahn coronaryarteryocclusionwithsharpbloodpressuredropduringgeneralanesthesiainductionacasereport
AT yujunpark coronaryarteryocclusionwithsharpbloodpressuredropduringgeneralanesthesiainductionacasereport
AT yeeunshin coronaryarteryocclusionwithsharpbloodpressuredropduringgeneralanesthesiainductionacasereport
AT chanhopark coronaryarteryocclusionwithsharpbloodpressuredropduringgeneralanesthesiainductionacasereport