Fever, seizures and encephalopathy: From bush fires to firestorms
Fever-associated seizures and febrile encephalopathy are common neurological problems in children. Infections of the nervous system are responsible for the majority of cases. However, there is a spectrum of infection-associated and inflammatory conditions associated with the triad of fever, seizures...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Annals of Indian Academy of Neurology |
| Subjects: | |
| Online Access: | http://www.annalsofian.org/article.asp?issn=0972-2327;year=2022;volume=25;issue=4;spage=587;epage=600;aulast=Kaur |
| _version_ | 1828133645896908800 |
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| author | Prabhjot Kaur Suvasini Sharma Ramesh Konanki Asuri N Prasad |
| author_facet | Prabhjot Kaur Suvasini Sharma Ramesh Konanki Asuri N Prasad |
| author_sort | Prabhjot Kaur |
| collection | DOAJ |
| description | Fever-associated seizures and febrile encephalopathy are common neurological problems in children. Infections of the nervous system are responsible for the majority of cases. However, there is a spectrum of infection-associated and inflammatory conditions associated with the triad of fever, seizures, and encephalopathy. Apart from complex febrile seizures and febrile status epilepticus, fever infection-related epilepsy syndrome of childhood (FIRES), infantile hemiconvulsion hemiplegia epilepsy syndrome (IHHE), acute encephalopathy with delayed diffusion restriction (AESD), acute necrotizing encephalopathy of childhood (ANE), and reversible splenial lesion syndrome (RESLES) are age-related clinical phenotypes of fever-related epilepsy and encephalopathy. Awareness of these entities is important for appropriate diagnosis and the prompt use of immunomodulatory/immunosuppressive therapies. In this review, we discuss the pathophysiology, clinical phenotypes, and management approaches of these fever-related seizure and encephalopathy states. |
| first_indexed | 2024-04-11T17:22:18Z |
| format | Article |
| id | doaj.art-62ec0a6ad7ca4b1fafb3ef3c0cde78d9 |
| institution | Directory Open Access Journal |
| issn | 0972-2327 1998-3549 |
| language | English |
| last_indexed | 2024-04-11T17:22:18Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Annals of Indian Academy of Neurology |
| spelling | doaj.art-62ec0a6ad7ca4b1fafb3ef3c0cde78d92022-12-22T04:12:28ZengWolters Kluwer Medknow PublicationsAnnals of Indian Academy of Neurology0972-23271998-35492022-01-0125458760010.4103/aian.aian_12_22Fever, seizures and encephalopathy: From bush fires to firestormsPrabhjot KaurSuvasini SharmaRamesh KonankiAsuri N PrasadFever-associated seizures and febrile encephalopathy are common neurological problems in children. Infections of the nervous system are responsible for the majority of cases. However, there is a spectrum of infection-associated and inflammatory conditions associated with the triad of fever, seizures, and encephalopathy. Apart from complex febrile seizures and febrile status epilepticus, fever infection-related epilepsy syndrome of childhood (FIRES), infantile hemiconvulsion hemiplegia epilepsy syndrome (IHHE), acute encephalopathy with delayed diffusion restriction (AESD), acute necrotizing encephalopathy of childhood (ANE), and reversible splenial lesion syndrome (RESLES) are age-related clinical phenotypes of fever-related epilepsy and encephalopathy. Awareness of these entities is important for appropriate diagnosis and the prompt use of immunomodulatory/immunosuppressive therapies. In this review, we discuss the pathophysiology, clinical phenotypes, and management approaches of these fever-related seizure and encephalopathy states.http://www.annalsofian.org/article.asp?issn=0972-2327;year=2022;volume=25;issue=4;spage=587;epage=600;aulast=Kauracute encephalopathy with delayed diffusion restriction (aesd)acute encephalopathy with repetitive refractory partial seizures (aerrps)acute necrotizing encephalopathy of childhood (ane)devastating epileptic encephalopathy in school-aged children (desc)encephalopathyepilepsyfebrile seizuresfebrile status epilepticusfeverfever infection-related epilepsy syndrome of childhood (fires)infantile hemiconvulsion hemiplegia epilepsy syndrome (ihhe)reversible splenial lesion syndrome (resles) |
| spellingShingle | Prabhjot Kaur Suvasini Sharma Ramesh Konanki Asuri N Prasad Fever, seizures and encephalopathy: From bush fires to firestorms Annals of Indian Academy of Neurology acute encephalopathy with delayed diffusion restriction (aesd) acute encephalopathy with repetitive refractory partial seizures (aerrps) acute necrotizing encephalopathy of childhood (ane) devastating epileptic encephalopathy in school-aged children (desc) encephalopathy epilepsy febrile seizures febrile status epilepticus fever fever infection-related epilepsy syndrome of childhood (fires) infantile hemiconvulsion hemiplegia epilepsy syndrome (ihhe) reversible splenial lesion syndrome (resles) |
| title | Fever, seizures and encephalopathy: From bush fires to firestorms |
| title_full | Fever, seizures and encephalopathy: From bush fires to firestorms |
| title_fullStr | Fever, seizures and encephalopathy: From bush fires to firestorms |
| title_full_unstemmed | Fever, seizures and encephalopathy: From bush fires to firestorms |
| title_short | Fever, seizures and encephalopathy: From bush fires to firestorms |
| title_sort | fever seizures and encephalopathy from bush fires to firestorms |
| topic | acute encephalopathy with delayed diffusion restriction (aesd) acute encephalopathy with repetitive refractory partial seizures (aerrps) acute necrotizing encephalopathy of childhood (ane) devastating epileptic encephalopathy in school-aged children (desc) encephalopathy epilepsy febrile seizures febrile status epilepticus fever fever infection-related epilepsy syndrome of childhood (fires) infantile hemiconvulsion hemiplegia epilepsy syndrome (ihhe) reversible splenial lesion syndrome (resles) |
| url | http://www.annalsofian.org/article.asp?issn=0972-2327;year=2022;volume=25;issue=4;spage=587;epage=600;aulast=Kaur |
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