Effect of Sodium Valproate on the Conformational Stability of the Visual G Protein-Coupled Receptor Rhodopsin

Effect of Sodium Valproate on the Conformational Stability of the Visual G Protein-Coupled Receptor Rhodopsin

Rhodopsin is the G protein-coupled receptor of rod photoreceptor cells that mediates vertebrate vision at low light intensities. Mutations in rhodopsin cause inherited retinal degenerative diseases such as retinitis pigmentosa. Several therapeutic strategies have attempted to address and counteract...

Full description

Bibliographic Details
Main Authors: Neda Razzaghi, Pol Fernandez-Gonzalez, Aina Mas-Sanchez, Guillem Vila-Julià, Juan Jesus Perez, Pere Garriga
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Molecules
Subjects:
rhodopsin
G protein-coupled receptor
sodium valproate
retinitis pigmentosa
conformational stability
Online Access:https://www.mdpi.com/1420-3049/26/10/3032

Similar Items

Similar Items