Traumatic brain injury alters the relationship between brain structure and episodic memory
Abstract Background Focal and diffuse pathology resulting from traumatic brain injury (TBI) often disrupts brain circuitry that is critical for episodic memory, including medial temporal lobe and prefrontal regions. Prior studies have focused on unitary accounts of temporal lobe function, associatin...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-06-01
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| Series: | Brain and Behavior |
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| Online Access: | https://doi.org/10.1002/brb3.3012 |
| _version_ | 1797802378315956224 |
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| author | Abbie S. Taing Matthew E. Mundy Jennie L. Ponsford Gershon Spitz |
| author_facet | Abbie S. Taing Matthew E. Mundy Jennie L. Ponsford Gershon Spitz |
| author_sort | Abbie S. Taing |
| collection | DOAJ |
| description | Abstract Background Focal and diffuse pathology resulting from traumatic brain injury (TBI) often disrupts brain circuitry that is critical for episodic memory, including medial temporal lobe and prefrontal regions. Prior studies have focused on unitary accounts of temporal lobe function, associating verbally learned material and brain morphology. Medial temporal lobe structures, however, are domain‐sensitive, preferentially supporting different visual stimuli. There has been little consideration of whether TBI preferentially disrupts the type of visually learned material and its association with cortical morphology following injury. Here, we investigated whether (1) episodic memory deficits differ according to the stimulus type, and (2) the pattern in memory performance can be linked to changes in cortical thickness. Methods Forty‐three individuals with moderate‐severe TBI and 38 demographically similar healthy controls completed a recognition task in which memory was assessed for three categories of stimuli: faces, scenes, and animals. The association between episodic memory accuracy on this task and cortical thickness was subsequently examined within and between groups. Results Our behavioral results support the notion of category‐specific impairments: the TBI group had significantly impaired accuracy for memory for faces and scenes, but not animals. Moreover, the association between cortical thickness and behavioral performance was only significant for faces between groups. Conclusion Taken together, these behavioral and structural findings provide support for an emergent memory account, and highlight that cortical thickness differentially affects episodic memory for specific categories of stimuli. |
| first_indexed | 2024-03-13T05:04:47Z |
| format | Article |
| id | doaj.art-62ef1abcce134d8d9185609d727f9aac |
| institution | Directory Open Access Journal |
| issn | 2162-3279 |
| language | English |
| last_indexed | 2024-03-13T05:04:47Z |
| publishDate | 2023-06-01 |
| publisher | Wiley |
| record_format | Article |
| series | Brain and Behavior |
| spelling | doaj.art-62ef1abcce134d8d9185609d727f9aac2023-06-16T18:11:55ZengWileyBrain and Behavior2162-32792023-06-01136n/an/a10.1002/brb3.3012Traumatic brain injury alters the relationship between brain structure and episodic memoryAbbie S. Taing0Matthew E. Mundy1Jennie L. Ponsford2Gershon Spitz3School of Psychological Sciences, Turner Institute for Brain and Mental Health Monash University Clayton Victoria AustraliaFaculty of Health and Education Torrens University Melbourne Victoria AustraliaSchool of Psychological Sciences, Turner Institute for Brain and Mental Health Monash University Clayton Victoria AustraliaSchool of Psychological Sciences, Turner Institute for Brain and Mental Health Monash University Clayton Victoria AustraliaAbstract Background Focal and diffuse pathology resulting from traumatic brain injury (TBI) often disrupts brain circuitry that is critical for episodic memory, including medial temporal lobe and prefrontal regions. Prior studies have focused on unitary accounts of temporal lobe function, associating verbally learned material and brain morphology. Medial temporal lobe structures, however, are domain‐sensitive, preferentially supporting different visual stimuli. There has been little consideration of whether TBI preferentially disrupts the type of visually learned material and its association with cortical morphology following injury. Here, we investigated whether (1) episodic memory deficits differ according to the stimulus type, and (2) the pattern in memory performance can be linked to changes in cortical thickness. Methods Forty‐three individuals with moderate‐severe TBI and 38 demographically similar healthy controls completed a recognition task in which memory was assessed for three categories of stimuli: faces, scenes, and animals. The association between episodic memory accuracy on this task and cortical thickness was subsequently examined within and between groups. Results Our behavioral results support the notion of category‐specific impairments: the TBI group had significantly impaired accuracy for memory for faces and scenes, but not animals. Moreover, the association between cortical thickness and behavioral performance was only significant for faces between groups. Conclusion Taken together, these behavioral and structural findings provide support for an emergent memory account, and highlight that cortical thickness differentially affects episodic memory for specific categories of stimuli.https://doi.org/10.1002/brb3.3012cortical thicknessemergent memory accountepisodic memoryMRItraumatic brain injury |
| spellingShingle | Abbie S. Taing Matthew E. Mundy Jennie L. Ponsford Gershon Spitz Traumatic brain injury alters the relationship between brain structure and episodic memory Brain and Behavior cortical thickness emergent memory account episodic memory MRI traumatic brain injury |
| title | Traumatic brain injury alters the relationship between brain structure and episodic memory |
| title_full | Traumatic brain injury alters the relationship between brain structure and episodic memory |
| title_fullStr | Traumatic brain injury alters the relationship between brain structure and episodic memory |
| title_full_unstemmed | Traumatic brain injury alters the relationship between brain structure and episodic memory |
| title_short | Traumatic brain injury alters the relationship between brain structure and episodic memory |
| title_sort | traumatic brain injury alters the relationship between brain structure and episodic memory |
| topic | cortical thickness emergent memory account episodic memory MRI traumatic brain injury |
| url | https://doi.org/10.1002/brb3.3012 |
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