Production of functionally active <it>Penicillium chrysogenum </it>isopenicillin N synthase in the yeast <it>Hansenula polymorpha</it>

Production of functionally active <it>Penicillium chrysogenum </it>isopenicillin N synthase in the yeast <it>Hansenula polymorpha</it>

<p>Abstract</p> <p>Background</p> <p>β-Lactams like penicillin and cephalosporin are among the oldest known antibiotics used against bacterial infections. Industrially, penicillin is produced by the filamentous fungus <it>Penicillium chrysogenum</it>. Our go...

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Bibliographic Details
Main Authors: Veenhuis Marten, van der Klei Ida J, Klaassen Paul, Bovenberg Roel AL, Gidijala Loknath, Kiel Jan AKW
Format: Article
Language:English
Published: BMC 2008-03-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/8/29

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