A Review of Exosomes in Regenerative Cosmetic Dermatology
Exosomes are the small extracellular vesicles secreted by almost all living cell types. They are a main component of cellular communication. To mediate intercellular communication, exosomes transport cellular cargo such as proteins, miRNA, nucleic acids, and various metabolites[Formula: see text]. A...
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| Format: | Article |
| Language: | English |
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World Scientific Publishing
2023-12-01
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| Series: | Molecular Frontiers Journal |
| Subjects: | |
| Online Access: | https://www.worldscientific.com/doi/10.1142/S2529732523400059 |
| _version_ | 1797383456741654528 |
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| author | Julia Miller Grace Chen Marie V Hayag |
| author_facet | Julia Miller Grace Chen Marie V Hayag |
| author_sort | Julia Miller |
| collection | DOAJ |
| description | Exosomes are the small extracellular vesicles secreted by almost all living cell types. They are a main component of cellular communication. To mediate intercellular communication, exosomes transport cellular cargo such as proteins, miRNA, nucleic acids, and various metabolites[Formula: see text]. Although specifics of their role in cellular physiology have yet to be uncovered, interest in exosomes and their functionality has exploded due to their diverse treatment and diagnostic capabilities. Already, numerous studies have proven the safety, efficacy, and therapeutic potential of exosomes in the treatment of cancers, neurodegenerative disorders, cardiovascular illness, and orthopedic diseases1. Due to their small size, high membrane permeability, and modifiability, exosomes are of the utmost therapeutic and diagnostic potential[Formula: see text]. As exosomes promote cellular regeneration, their role in general dermatology as well as cosmetic dermatology has become prominent. In the past few years, cosmetic dermatology research proves the potential of exosomes in the processes of skin rejuvenation, postprocedural care, and dermal maintenance. Some of the most popular modalities of treatment include hair restoration, photorejuvenation, daily maintenance, and antiaging. This paper will discuss the biological function, isolation methods, and therapeutic role of mesenchymal stem cell-and platelet-derived exosomes in cosmetic dermatology. |
| first_indexed | 2024-03-08T21:21:16Z |
| format | Article |
| id | doaj.art-62f3499c36824258a023e7d1eaa7fac3 |
| institution | Directory Open Access Journal |
| issn | 2529-7325 2529-7333 |
| language | English |
| last_indexed | 2024-03-08T21:21:16Z |
| publishDate | 2023-12-01 |
| publisher | World Scientific Publishing |
| record_format | Article |
| series | Molecular Frontiers Journal |
| spelling | doaj.art-62f3499c36824258a023e7d1eaa7fac32023-12-21T10:18:33ZengWorld Scientific PublishingMolecular Frontiers Journal2529-73252529-73332023-12-010701n02647010.1142/S2529732523400059A Review of Exosomes in Regenerative Cosmetic DermatologyJulia Miller0Grace Chen1Marie V Hayag2Mount Sinai Hospital, Fifth Avenue Aesthetics, 875 Fifth Avenue New York, NY 10065, USAMount Sinai Hospital, Fifth Avenue Aesthetics, 875 Fifth Avenue New York, NY 10065, USAMount Sinai Hospital, Fifth Avenue Aesthetics, 875 Fifth Avenue New York, NY 10065, USAExosomes are the small extracellular vesicles secreted by almost all living cell types. They are a main component of cellular communication. To mediate intercellular communication, exosomes transport cellular cargo such as proteins, miRNA, nucleic acids, and various metabolites[Formula: see text]. Although specifics of their role in cellular physiology have yet to be uncovered, interest in exosomes and their functionality has exploded due to their diverse treatment and diagnostic capabilities. Already, numerous studies have proven the safety, efficacy, and therapeutic potential of exosomes in the treatment of cancers, neurodegenerative disorders, cardiovascular illness, and orthopedic diseases1. Due to their small size, high membrane permeability, and modifiability, exosomes are of the utmost therapeutic and diagnostic potential[Formula: see text]. As exosomes promote cellular regeneration, their role in general dermatology as well as cosmetic dermatology has become prominent. In the past few years, cosmetic dermatology research proves the potential of exosomes in the processes of skin rejuvenation, postprocedural care, and dermal maintenance. Some of the most popular modalities of treatment include hair restoration, photorejuvenation, daily maintenance, and antiaging. This paper will discuss the biological function, isolation methods, and therapeutic role of mesenchymal stem cell-and platelet-derived exosomes in cosmetic dermatology.https://www.worldscientific.com/doi/10.1142/S2529732523400059Regenerative MedicineWound HealingExosomesAnti-AgingAnti-inflammatorySkin Rejuvenation |
| spellingShingle | Julia Miller Grace Chen Marie V Hayag A Review of Exosomes in Regenerative Cosmetic Dermatology Molecular Frontiers Journal Regenerative Medicine Wound Healing Exosomes Anti-Aging Anti-inflammatory Skin Rejuvenation |
| title | A Review of Exosomes in Regenerative Cosmetic Dermatology |
| title_full | A Review of Exosomes in Regenerative Cosmetic Dermatology |
| title_fullStr | A Review of Exosomes in Regenerative Cosmetic Dermatology |
| title_full_unstemmed | A Review of Exosomes in Regenerative Cosmetic Dermatology |
| title_short | A Review of Exosomes in Regenerative Cosmetic Dermatology |
| title_sort | review of exosomes in regenerative cosmetic dermatology |
| topic | Regenerative Medicine Wound Healing Exosomes Anti-Aging Anti-inflammatory Skin Rejuvenation |
| url | https://www.worldscientific.com/doi/10.1142/S2529732523400059 |
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