Current Applications and Challenges of Next-Generation Sequencing in Plasma Circulating Tumour DNA of Ovarian Cancer

Current Applications and Challenges of Next-Generation Sequencing in Plasma Circulating Tumour DNA of Ovarian Cancer

Circulating tumour DNA (ctDNA) facilitates longitudinal study of the tumour genome, which, unlike tumour tissue biopsies, globally reflects intratumor and intermetastatis heterogeneity. Despite its costs, next-generation sequencing (NGS) has revolutionised the study of ctDNA, ensuring a more compreh...

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Bibliographic Details
Main Authors: Ricardo Roque, Ilda Patrícia Ribeiro, Margarida Figueiredo-Dias, Charlie Gourley, Isabel Marques Carreira
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Biology
Subjects:
ovarian cancer
liquid biopsy
circulating tumour DNA
next-generation sequencing
Online Access:https://www.mdpi.com/2079-7737/13/2/88

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