Association between using a prehospital assessment unit and hospital admission and mortality: a matched cohort study

Objectives This study aimed to compare hospital admission and 30-day mortality between patients assessed by the prehospital assessment unit (PAU) and patients not assessed by the PAU.Design This was a matched cohort study.Setting This study was conducted between November 2021 and October 2022 in Reg...

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Main Authors: Stig Nikolaj Fasmer Blomberg, Daniel Hägi-Pedersen, Niklas Breindahl, Signe Amalie Wolthers, Sair Anjum, Annette Ersbøll, Lars Bredevang Andersen, Helle Collatz Christensen
Format: Article
Language:English
Published: BMJ Publishing Group 2023-09-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/13/9/e075592.full
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author Stig Nikolaj Fasmer Blomberg
Daniel Hägi-Pedersen
Niklas Breindahl
Signe Amalie Wolthers
Sair Anjum
Annette Ersbøll
Lars Bredevang Andersen
Helle Collatz Christensen
author_facet Stig Nikolaj Fasmer Blomberg
Daniel Hägi-Pedersen
Niklas Breindahl
Signe Amalie Wolthers
Sair Anjum
Annette Ersbøll
Lars Bredevang Andersen
Helle Collatz Christensen
author_sort Stig Nikolaj Fasmer Blomberg
collection DOAJ
description Objectives This study aimed to compare hospital admission and 30-day mortality between patients assessed by the prehospital assessment unit (PAU) and patients not assessed by the PAU.Design This was a matched cohort study.Setting This study was conducted between November 2021 and October 2022 in Region Zealand, Denmark.Participants 989 patients aged >18, assessed by the PAU, were identified, and 9860 patients not assessed by the PAU were selected from the emergency calls using exposure density sampling.Exposure Patients assessed by the PAU. The PAU is operated by paramedics with access to point-of-care test facilities. The PAU is an alternative response vehicle without the capability of transporting patients.Primary and secondary outcome measures The primary outcome was hospital admission within 48 hours after the initial call. The key secondary outcomes were admission within 7 days, 30-day mortality and admission within 6 hours. Descriptive statistical analyses were conducted, and logistic regression models were used to estimate adjusted OR (aOR) and 95% CI.Results Among the PAU assessed, 44.1% were admitted within 48 hours, compared with 72.9% of the non-PAU assessed, p<0.001. The multivariable analysis showed a lower risk of admission within 48 hours and 7 days among the PAU patients, aOR 0.31 (95% CI 0.26 to 0.38) and aOR 0.50 (95% CI 0.38 to 0.64), respectively. The 30-day mortality rate was 3.8% in the PAU-assessed patients vs 5.5% in the non-PAU-assessed patients, p=0.03. In the multivariable analysis, no significant difference was found in mortality aOR 0.99 (95% CI 0.71 to 1.42). No deaths were observed in PAU-assessed patients without subsequent follow-up.Conclusion The recently introduced PAU aims for patient-centred emergency care. The PAU-assessed patients had reduced admissions within 48 hours and 7 days after the initial call. Study findings indicate that the PAU is safe since we identified no significant differences in 30-day mortality.Trial registration number NCT05654909.
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spelling doaj.art-62ffd124253f4b5e9653f04a7ca86ad22023-10-02T00:00:06ZengBMJ Publishing GroupBMJ Open2044-60552023-09-0113910.1136/bmjopen-2023-075592Association between using a prehospital assessment unit and hospital admission and mortality: a matched cohort studyStig Nikolaj Fasmer Blomberg0Daniel Hägi-Pedersen1Niklas Breindahl2Signe Amalie Wolthers3Sair Anjum4Annette Ersbøll5Lars Bredevang Andersen6Helle Collatz Christensen7Prehospital Center, Region Zealand, Naestved, DenmarkDepartment of Anaesthesiology, Slagelse University Hospital, Slagelse, DenmarkPrehospital Center, Region Zealand, Naestved, DenmarkPrehospital Center, Region Zealand, Naestved, DenmarkDepartment of Anaesthesiology, Slagelse University Hospital, Slagelse, DenmarkUniversity of Southern Denmark National Institute of Public Health, Copenhagen, DenmarkPrehospital Center, Region Zealand, Naestved, DenmarkPrehospital Center, Region Zealand, Naestved, DenmarkObjectives This study aimed to compare hospital admission and 30-day mortality between patients assessed by the prehospital assessment unit (PAU) and patients not assessed by the PAU.Design This was a matched cohort study.Setting This study was conducted between November 2021 and October 2022 in Region Zealand, Denmark.Participants 989 patients aged >18, assessed by the PAU, were identified, and 9860 patients not assessed by the PAU were selected from the emergency calls using exposure density sampling.Exposure Patients assessed by the PAU. The PAU is operated by paramedics with access to point-of-care test facilities. The PAU is an alternative response vehicle without the capability of transporting patients.Primary and secondary outcome measures The primary outcome was hospital admission within 48 hours after the initial call. The key secondary outcomes were admission within 7 days, 30-day mortality and admission within 6 hours. Descriptive statistical analyses were conducted, and logistic regression models were used to estimate adjusted OR (aOR) and 95% CI.Results Among the PAU assessed, 44.1% were admitted within 48 hours, compared with 72.9% of the non-PAU assessed, p<0.001. The multivariable analysis showed a lower risk of admission within 48 hours and 7 days among the PAU patients, aOR 0.31 (95% CI 0.26 to 0.38) and aOR 0.50 (95% CI 0.38 to 0.64), respectively. The 30-day mortality rate was 3.8% in the PAU-assessed patients vs 5.5% in the non-PAU-assessed patients, p=0.03. In the multivariable analysis, no significant difference was found in mortality aOR 0.99 (95% CI 0.71 to 1.42). No deaths were observed in PAU-assessed patients without subsequent follow-up.Conclusion The recently introduced PAU aims for patient-centred emergency care. The PAU-assessed patients had reduced admissions within 48 hours and 7 days after the initial call. Study findings indicate that the PAU is safe since we identified no significant differences in 30-day mortality.Trial registration number NCT05654909.https://bmjopen.bmj.com/content/13/9/e075592.full
spellingShingle Stig Nikolaj Fasmer Blomberg
Daniel Hägi-Pedersen
Niklas Breindahl
Signe Amalie Wolthers
Sair Anjum
Annette Ersbøll
Lars Bredevang Andersen
Helle Collatz Christensen
Association between using a prehospital assessment unit and hospital admission and mortality: a matched cohort study
BMJ Open
title Association between using a prehospital assessment unit and hospital admission and mortality: a matched cohort study
title_full Association between using a prehospital assessment unit and hospital admission and mortality: a matched cohort study
title_fullStr Association between using a prehospital assessment unit and hospital admission and mortality: a matched cohort study
title_full_unstemmed Association between using a prehospital assessment unit and hospital admission and mortality: a matched cohort study
title_short Association between using a prehospital assessment unit and hospital admission and mortality: a matched cohort study
title_sort association between using a prehospital assessment unit and hospital admission and mortality a matched cohort study
url https://bmjopen.bmj.com/content/13/9/e075592.full
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