Psychobiotics-like Activity as a Novel Treatment against Dry Scalp Related-White Flakes Production with <i>Pogostemon cablin</i> Leaf Extract
Microbiome supplementation initially targeted the gut microbiota but has since been extended to the skin. A new category, psychobiotics, defined beneficial compounds with a positive action on microbiota, providing benefits to the host’s mental health. <i>Pogostemon cablin</i> leaf extrac...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-09-01
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| Series: | Cosmetics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-9284/10/5/130 |
| _version_ | 1827721301645590528 |
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| author | Marie Meunier Emilie Chapuis Cyrille Jarrin Julia Brooks Heather Carolan Jean Tiguemounine Carole Lambert Bénédicte Sennelier-Portet Catherine Zanchetta Amandine Scandolera Romain Reynaud |
| author_facet | Marie Meunier Emilie Chapuis Cyrille Jarrin Julia Brooks Heather Carolan Jean Tiguemounine Carole Lambert Bénédicte Sennelier-Portet Catherine Zanchetta Amandine Scandolera Romain Reynaud |
| author_sort | Marie Meunier |
| collection | DOAJ |
| description | Microbiome supplementation initially targeted the gut microbiota but has since been extended to the skin. A new category, psychobiotics, defined beneficial compounds with a positive action on microbiota, providing benefits to the host’s mental health. <i>Pogostemon cablin</i> leaf extract, proven to alleviate scalp dryness, was clinically evaluated on volunteers presenting dry scalp with flakes. A metagenomics study and sebum production analysis were performed, coupled to flakes scoring. The benefits of <i>Pogostemon cablin</i> leaf extract on emotions were assessed through three neuroscientific methods. Through this study, we proved that the skin microbiota of dry scalp was imbalanced, with increased alpha diversity and decreased <i>Cutibacterium</i> relative abundance compared to oilier skin. After applying our ingredient for one month, microbiota was rebalanced with a decrease in alpha diversity and increase in <i>Cutibacterium</i> relative abundance compared to the initial profile. Microbiota rebalancing led to an increase in scalp sebum and decrease in dry flakes compared to the start of the study. This global rebalancing improved the emotional state of people with scalp dryness who expressed more positive emotions after treatment. |
| first_indexed | 2024-03-10T21:19:41Z |
| format | Article |
| id | doaj.art-6303bdaaa9fc406396b38ca533fe3f69 |
| institution | Directory Open Access Journal |
| issn | 2079-9284 |
| language | English |
| last_indexed | 2024-03-10T21:19:41Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cosmetics |
| spelling | doaj.art-6303bdaaa9fc406396b38ca533fe3f692023-11-19T16:08:25ZengMDPI AGCosmetics2079-92842023-09-0110513010.3390/cosmetics10050130Psychobiotics-like Activity as a Novel Treatment against Dry Scalp Related-White Flakes Production with <i>Pogostemon cablin</i> Leaf ExtractMarie Meunier0Emilie Chapuis1Cyrille Jarrin2Julia Brooks3Heather Carolan4Jean Tiguemounine5Carole Lambert6Bénédicte Sennelier-Portet7Catherine Zanchetta8Amandine Scandolera9Romain Reynaud10Givaudan Active Beauty, 51110 Pomacle, FranceGivaudan Active Beauty, 51110 Pomacle, FranceGivaudan Active Beauty, 31400 Toulouse, FranceGivaudan UK, Ashford TN24 0LT, UKGivaudan UK, Ashford TN24 0LT, UKPolyclinique Courlancy, 51100 Reims, FranceGivaudan Active Beauty, 31400 Toulouse, FranceGivaudan France Naturals, 84911 Avignon, FranceGivaudan Active Beauty, 31400 Toulouse, FranceGivaudan Active Beauty, 51110 Pomacle, FranceGivaudan Active Beauty, 31400 Toulouse, FranceMicrobiome supplementation initially targeted the gut microbiota but has since been extended to the skin. A new category, psychobiotics, defined beneficial compounds with a positive action on microbiota, providing benefits to the host’s mental health. <i>Pogostemon cablin</i> leaf extract, proven to alleviate scalp dryness, was clinically evaluated on volunteers presenting dry scalp with flakes. A metagenomics study and sebum production analysis were performed, coupled to flakes scoring. The benefits of <i>Pogostemon cablin</i> leaf extract on emotions were assessed through three neuroscientific methods. Through this study, we proved that the skin microbiota of dry scalp was imbalanced, with increased alpha diversity and decreased <i>Cutibacterium</i> relative abundance compared to oilier skin. After applying our ingredient for one month, microbiota was rebalanced with a decrease in alpha diversity and increase in <i>Cutibacterium</i> relative abundance compared to the initial profile. Microbiota rebalancing led to an increase in scalp sebum and decrease in dry flakes compared to the start of the study. This global rebalancing improved the emotional state of people with scalp dryness who expressed more positive emotions after treatment.https://www.mdpi.com/2079-9284/10/5/130scalp disordersemotionsneurocosmeticspsychobioticsskin-brain axis<i>Pogostemon cablin</i> |
| spellingShingle | Marie Meunier Emilie Chapuis Cyrille Jarrin Julia Brooks Heather Carolan Jean Tiguemounine Carole Lambert Bénédicte Sennelier-Portet Catherine Zanchetta Amandine Scandolera Romain Reynaud Psychobiotics-like Activity as a Novel Treatment against Dry Scalp Related-White Flakes Production with <i>Pogostemon cablin</i> Leaf Extract Cosmetics scalp disorders emotions neurocosmetics psychobiotics skin-brain axis <i>Pogostemon cablin</i> |
| title | Psychobiotics-like Activity as a Novel Treatment against Dry Scalp Related-White Flakes Production with <i>Pogostemon cablin</i> Leaf Extract |
| title_full | Psychobiotics-like Activity as a Novel Treatment against Dry Scalp Related-White Flakes Production with <i>Pogostemon cablin</i> Leaf Extract |
| title_fullStr | Psychobiotics-like Activity as a Novel Treatment against Dry Scalp Related-White Flakes Production with <i>Pogostemon cablin</i> Leaf Extract |
| title_full_unstemmed | Psychobiotics-like Activity as a Novel Treatment against Dry Scalp Related-White Flakes Production with <i>Pogostemon cablin</i> Leaf Extract |
| title_short | Psychobiotics-like Activity as a Novel Treatment against Dry Scalp Related-White Flakes Production with <i>Pogostemon cablin</i> Leaf Extract |
| title_sort | psychobiotics like activity as a novel treatment against dry scalp related white flakes production with i pogostemon cablin i leaf extract |
| topic | scalp disorders emotions neurocosmetics psychobiotics skin-brain axis <i>Pogostemon cablin</i> |
| url | https://www.mdpi.com/2079-9284/10/5/130 |
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