Statistical signal detection methods

Modern approaches to solving the problem of detecting signals about the safety of drugs are presented. The basic concept, provided the detection of signals by quantitative methods in databases of spontaneous messages is presented. Approaches to the interpretation of the signal about disproportionali...

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Main Authors: K. E. Zatolochina, I. I. Snegireva, E. O. Zhuravleva, M. A. Darmostukova, R. N. Alyautdin
Format: Article
Language:Russian
Published: Ministry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2018-02-01
Series:Безопасность и риск фармакотерапии
Subjects:
Online Access:https://www.risksafety.ru/jour/article/view/72
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author K. E. Zatolochina
I. I. Snegireva
E. O. Zhuravleva
M. A. Darmostukova
R. N. Alyautdin
author_facet K. E. Zatolochina
I. I. Snegireva
E. O. Zhuravleva
M. A. Darmostukova
R. N. Alyautdin
author_sort K. E. Zatolochina
collection DOAJ
description Modern approaches to solving the problem of detecting signals about the safety of drugs are presented. The basic concept, provided the detection of signals by quantitative methods in databases of spontaneous messages is presented. Approaches to the interpretation of the signal about disproportionality are described.
first_indexed 2024-03-08T22:27:20Z
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2619-1164
language Russian
last_indexed 2025-03-14T10:50:59Z
publishDate 2018-02-01
publisher Ministry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products»
record_format Article
series Безопасность и риск фармакотерапии
spelling doaj.art-6304f261580249ee818c44bf9ae7ae932025-03-02T10:50:02ZrusMinistry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products»Безопасность и риск фармакотерапии2312-78212619-11642018-02-0152768272Statistical signal detection methodsK. E. Zatolochina0I. I. Snegireva1E. O. Zhuravleva2M. A. Darmostukova3R. N. Alyautdin4Scientific Centre for Expert Evaluation of Medicinal ProductsScientific Centre for Expert Evaluation of Medicinal ProductsScientific Centre for Expert Evaluation of Medicinal ProductsScientific Centre for Expert Evaluation of Medicinal ProductsScientific Centre for Expert Evaluation of Medicinal ProductsModern approaches to solving the problem of detecting signals about the safety of drugs are presented. The basic concept, provided the detection of signals by quantitative methods in databases of spontaneous messages is presented. Approaches to the interpretation of the signal about disproportionality are described.https://www.risksafety.ru/jour/article/view/72методы диспропорциональностиколичественные методысигналбезопасность лекарственных средствфармаконадзорdisproportionality methodsquantitative methodssignaldrug safetypharmacovigilance
spellingShingle K. E. Zatolochina
I. I. Snegireva
E. O. Zhuravleva
M. A. Darmostukova
R. N. Alyautdin
Statistical signal detection methods
Безопасность и риск фармакотерапии
методы диспропорциональности
количественные методы
сигнал
безопасность лекарственных средств
фармаконадзор
disproportionality methods
quantitative methods
signal
drug safety
pharmacovigilance
title Statistical signal detection methods
title_full Statistical signal detection methods
title_fullStr Statistical signal detection methods
title_full_unstemmed Statistical signal detection methods
title_short Statistical signal detection methods
title_sort statistical signal detection methods
topic методы диспропорциональности
количественные методы
сигнал
безопасность лекарственных средств
фармаконадзор
disproportionality methods
quantitative methods
signal
drug safety
pharmacovigilance
url https://www.risksafety.ru/jour/article/view/72
work_keys_str_mv AT kezatolochina statisticalsignaldetectionmethods
AT iisnegireva statisticalsignaldetectionmethods
AT eozhuravleva statisticalsignaldetectionmethods
AT madarmostukova statisticalsignaldetectionmethods
AT rnalyautdin statisticalsignaldetectionmethods