Chronic Vestibular Hypofunction Is Associated with Impaired Sleep: Results from the DizzyReg Patient Registry
Temporary or permanent vestibular hypofunction has been hypothesized to affect circadian rhythm, sleep, and thermoregulation. Chronic or long-term vestibular disorders such as unilateral vestibular hypofunction may have an even greater negative impact on sleep quality than acute vestibular problems....
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-09-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/18/5903 |
| _version_ | 1797579508342063104 |
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| author | Benedict Katzenberger Fiona Brosch Stéphane Besnard Eva Grill |
| author_facet | Benedict Katzenberger Fiona Brosch Stéphane Besnard Eva Grill |
| author_sort | Benedict Katzenberger |
| collection | DOAJ |
| description | Temporary or permanent vestibular hypofunction has been hypothesized to affect circadian rhythm, sleep, and thermoregulation. Chronic or long-term vestibular disorders such as unilateral vestibular hypofunction may have an even greater negative impact on sleep quality than acute vestibular problems. This study examines self-reported sleep quality, as assessed by the Pittsburgh Sleep Quality Index (PSQI), and its association with vestibular symptom duration in a group of patients with vestibular disorders. We used data from the cross-sectional DizzyReg patient registry of the German Center for Vertigo and Balance Disorders outpatient clinic. Vestibular diagnoses were ascertained based on the International Classification of Vestibular Disorders. A total of 137 patients were included (60% female, mean age 55.4 years, standard deviation, SD, 16.7). The mean PSQI total score was 6.3 (SD = 3.2), with 51% reporting overall poor sleep quality. Patients who had vertigo for two years or longer reported significantly poorer global sleep quality (63% vs. 37%, <i>p</i> = 0.021) and significantly more difficulties with sleep latency (79% vs. 56%, <i>p</i> = 0.013) and sleep efficiency (56% vs. 34%, <i>p</i> = 0.022). The association of poor sleep quality with a longer duration of vertigo remained significant after multivariable adjustment. Further research should investigate the interaction of vestibular disorders, sleep, and their potential mechanisms. |
| first_indexed | 2024-03-10T22:37:11Z |
| format | Article |
| id | doaj.art-63089b5fabe246a2b052ece30857c632 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T22:37:11Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-63089b5fabe246a2b052ece30857c6322023-11-19T11:19:01ZengMDPI AGJournal of Clinical Medicine2077-03832023-09-011218590310.3390/jcm12185903Chronic Vestibular Hypofunction Is Associated with Impaired Sleep: Results from the DizzyReg Patient RegistryBenedict Katzenberger0Fiona Brosch1Stéphane Besnard2Eva Grill3Institute for Medical Information Processing, Biometry and Epidemiology (IBE), Faculty of Medicine, LMU Munich, 81377 Munich, GermanyInstitute for Medical Information Processing, Biometry and Epidemiology (IBE), Faculty of Medicine, LMU Munich, 81377 Munich, GermanyLaboratory of Cognitive Neurosciences, UMR7291, Team Pathophysiology and Therapy of Vestibular Disorders, Centre National de la Recherche Scientifique (CNRS), Aix Marseille University, 13331 Marseille, FranceInstitute for Medical Information Processing, Biometry and Epidemiology (IBE), Faculty of Medicine, LMU Munich, 81377 Munich, GermanyTemporary or permanent vestibular hypofunction has been hypothesized to affect circadian rhythm, sleep, and thermoregulation. Chronic or long-term vestibular disorders such as unilateral vestibular hypofunction may have an even greater negative impact on sleep quality than acute vestibular problems. This study examines self-reported sleep quality, as assessed by the Pittsburgh Sleep Quality Index (PSQI), and its association with vestibular symptom duration in a group of patients with vestibular disorders. We used data from the cross-sectional DizzyReg patient registry of the German Center for Vertigo and Balance Disorders outpatient clinic. Vestibular diagnoses were ascertained based on the International Classification of Vestibular Disorders. A total of 137 patients were included (60% female, mean age 55.4 years, standard deviation, SD, 16.7). The mean PSQI total score was 6.3 (SD = 3.2), with 51% reporting overall poor sleep quality. Patients who had vertigo for two years or longer reported significantly poorer global sleep quality (63% vs. 37%, <i>p</i> = 0.021) and significantly more difficulties with sleep latency (79% vs. 56%, <i>p</i> = 0.013) and sleep efficiency (56% vs. 34%, <i>p</i> = 0.022). The association of poor sleep quality with a longer duration of vertigo remained significant after multivariable adjustment. Further research should investigate the interaction of vestibular disorders, sleep, and their potential mechanisms.https://www.mdpi.com/2077-0383/12/18/5903balanceposturesleep disordercompensationvertigodizziness |
| spellingShingle | Benedict Katzenberger Fiona Brosch Stéphane Besnard Eva Grill Chronic Vestibular Hypofunction Is Associated with Impaired Sleep: Results from the DizzyReg Patient Registry Journal of Clinical Medicine balance posture sleep disorder compensation vertigo dizziness |
| title | Chronic Vestibular Hypofunction Is Associated with Impaired Sleep: Results from the DizzyReg Patient Registry |
| title_full | Chronic Vestibular Hypofunction Is Associated with Impaired Sleep: Results from the DizzyReg Patient Registry |
| title_fullStr | Chronic Vestibular Hypofunction Is Associated with Impaired Sleep: Results from the DizzyReg Patient Registry |
| title_full_unstemmed | Chronic Vestibular Hypofunction Is Associated with Impaired Sleep: Results from the DizzyReg Patient Registry |
| title_short | Chronic Vestibular Hypofunction Is Associated with Impaired Sleep: Results from the DizzyReg Patient Registry |
| title_sort | chronic vestibular hypofunction is associated with impaired sleep results from the dizzyreg patient registry |
| topic | balance posture sleep disorder compensation vertigo dizziness |
| url | https://www.mdpi.com/2077-0383/12/18/5903 |
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