Cell sex affects extracellular matrix protein expression and proliferation of smooth muscle progenitor cells derived from human pluripotent stem cells

Cell sex affects extracellular matrix protein expression and proliferation of smooth muscle progenitor cells derived from human pluripotent stem cells

Abstract Background Smooth muscle progenitor cells (pSMCs) differentiated from human pluripotent stem cells (hPSCs) hold great promise for treating diseases or degenerative conditions involving smooth muscle pathologies. However, the therapeutic potential of pSMCs derived from men and women may be v...

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Bibliographic Details
Main Authors: Yanhui Li, Yan Wen, Morgaine Green, Elise K. Cabral, Prachi Wani, Fan Zhang, Yi Wei, Thomas M. Baer, Bertha Chen
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Stem Cell Research & Therapy
Subjects:
Sex differences
Smooth muscle progenitor cell
Pluripotent stem cell
Estrogen
Extracellular matrix
Cell proliferation
Online Access:http://link.springer.com/article/10.1186/s13287-017-0606-2

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