Molybdenum‐Based Nanomaterials for Photothermal Cancer Therapy
Molybdenum (Mo) is a trace dietary element that is essential for human survival. Several molybdenum‐containing enzymes (e.g., aldehyde oxidase, xanthine oxidase and sulfite oxidase) are associated with key metabolic activities in the body. Molybdenum‐based nanomaterials (Mo‐NMs), including molybdenu...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley-VCH
2022-11-01
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| Series: | Advanced NanoBiomed Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/anbr.202200065 |
| _version_ | 1811221726171758592 |
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| author | Zhan Zhou Xiangqian Li Tingting Hu Baoli Xue Hong Chen Lufang Ma Ruizheng Liang Chaoliang Tan |
| author_facet | Zhan Zhou Xiangqian Li Tingting Hu Baoli Xue Hong Chen Lufang Ma Ruizheng Liang Chaoliang Tan |
| author_sort | Zhan Zhou |
| collection | DOAJ |
| description | Molybdenum (Mo) is a trace dietary element that is essential for human survival. Several molybdenum‐containing enzymes (e.g., aldehyde oxidase, xanthine oxidase and sulfite oxidase) are associated with key metabolic activities in the body. Molybdenum‐based nanomaterials (Mo‐NMs), including molybdenum dichalcogenides, molybdenum oxides, molybdenum‐based polyoxometalates, and molybdenum‐based nanocomposites, have been extensively explored in biomedical applications including photothermal therapy (PTT) because of their unique chemical and physical properties as well as excellent biocompatibility and biodegradability. PTT, which relies on converting the near‐infrared (NIR) light energy into thermal energy to achieve therapeutic effects, has attracted considerable attention in past decades for cancer treatment because of its localized and trigger‐activated therapeutic effects. In this review, the state‐of‐the‐art progress on Mo‐NMs for photothermal cancer treatment is summarized. The classification, synthesis, and surface functionalization of Mo‐NMs are first introduced. Then the discussion of PTT and PTT‐combined therapies of Mo‐NMs for effective cancer treatment is focused on. Following that, the toxicity assessment of Mo‐NMs is also discussed. Finally, a short discussion on the challenges and future prospects in this field is presented. |
| first_indexed | 2024-04-12T08:04:20Z |
| format | Article |
| id | doaj.art-630e264de2474698a49bf8f8256520d4 |
| institution | Directory Open Access Journal |
| issn | 2699-9307 |
| language | English |
| last_indexed | 2024-04-12T08:04:20Z |
| publishDate | 2022-11-01 |
| publisher | Wiley-VCH |
| record_format | Article |
| series | Advanced NanoBiomed Research |
| spelling | doaj.art-630e264de2474698a49bf8f8256520d42022-12-22T03:41:12ZengWiley-VCHAdvanced NanoBiomed Research2699-93072022-11-01211n/an/a10.1002/anbr.202200065Molybdenum‐Based Nanomaterials for Photothermal Cancer TherapyZhan Zhou0Xiangqian Li1Tingting Hu2Baoli Xue3Hong Chen4Lufang Ma5Ruizheng Liang6Chaoliang Tan7College of Chemistry and Chemical Engineering Henan Key Laboratory of Function-Oriented Porous Materials Luoyang Normal University Luoyang 471934 P.R. ChinaSchool of Chemical and Environmental Engineering (Key Lab of Ecological Restoration in Hilly Areas) Pingdingshan University Pingdingshan 467000 P.R. ChinaState Key Laboratory of Chemical Resource Engineering Beijing Advanced Innovation Center for Soft Matter Science and Engineering Beijing University of Chemical Technology Beijing 100029 P.R. ChinaLuoyang Key Laboratory of Organic Functional Molecules College of Food and Drug Luoyang Normal University Luoyang 471934 P.R. ChinaLuoyang Key Laboratory of Organic Functional Molecules College of Food and Drug Luoyang Normal University Luoyang 471934 P.R. ChinaCollege of Chemistry and Chemical Engineering Henan Key Laboratory of Function-Oriented Porous Materials Luoyang Normal University Luoyang 471934 P.R. ChinaState Key Laboratory of Chemical Resource Engineering Beijing Advanced Innovation Center for Soft Matter Science and Engineering Beijing University of Chemical Technology Beijing 100029 P.R. ChinaCenter of Super-Diamond and Advanced Films (COSDAF) Department of Chemistry City University of Hong Kong Kowloon Hong Kong SAR 999077 P.R. ChinaMolybdenum (Mo) is a trace dietary element that is essential for human survival. Several molybdenum‐containing enzymes (e.g., aldehyde oxidase, xanthine oxidase and sulfite oxidase) are associated with key metabolic activities in the body. Molybdenum‐based nanomaterials (Mo‐NMs), including molybdenum dichalcogenides, molybdenum oxides, molybdenum‐based polyoxometalates, and molybdenum‐based nanocomposites, have been extensively explored in biomedical applications including photothermal therapy (PTT) because of their unique chemical and physical properties as well as excellent biocompatibility and biodegradability. PTT, which relies on converting the near‐infrared (NIR) light energy into thermal energy to achieve therapeutic effects, has attracted considerable attention in past decades for cancer treatment because of its localized and trigger‐activated therapeutic effects. In this review, the state‐of‐the‐art progress on Mo‐NMs for photothermal cancer treatment is summarized. The classification, synthesis, and surface functionalization of Mo‐NMs are first introduced. Then the discussion of PTT and PTT‐combined therapies of Mo‐NMs for effective cancer treatment is focused on. Following that, the toxicity assessment of Mo‐NMs is also discussed. Finally, a short discussion on the challenges and future prospects in this field is presented.https://doi.org/10.1002/anbr.202200065cancer theranosticscombined therapiesmolybdenum dichalcogenidesmolybdenum oxidesphotothermal therapy |
| spellingShingle | Zhan Zhou Xiangqian Li Tingting Hu Baoli Xue Hong Chen Lufang Ma Ruizheng Liang Chaoliang Tan Molybdenum‐Based Nanomaterials for Photothermal Cancer Therapy Advanced NanoBiomed Research cancer theranostics combined therapies molybdenum dichalcogenides molybdenum oxides photothermal therapy |
| title | Molybdenum‐Based Nanomaterials for Photothermal Cancer Therapy |
| title_full | Molybdenum‐Based Nanomaterials for Photothermal Cancer Therapy |
| title_fullStr | Molybdenum‐Based Nanomaterials for Photothermal Cancer Therapy |
| title_full_unstemmed | Molybdenum‐Based Nanomaterials for Photothermal Cancer Therapy |
| title_short | Molybdenum‐Based Nanomaterials for Photothermal Cancer Therapy |
| title_sort | molybdenum based nanomaterials for photothermal cancer therapy |
| topic | cancer theranostics combined therapies molybdenum dichalcogenides molybdenum oxides photothermal therapy |
| url | https://doi.org/10.1002/anbr.202200065 |
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