Acute liver failure in a military recruit treated with valproic acid and harboring a previously unrecognized POLG-1 mutation
Patients with mutations in the POLG-1 gene often are afflicted with drug-resistant seizures at an early age and have an increased risk of valproic acid-induced acute liver failure. Severe valproate hepatotoxicity most commonly arises in children within the first 3 months of treatment with an overall...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2019-01-01
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| Series: | Epilepsy & Behavior Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589986419301364 |