Global lysine methylome profiling using systematically characterized affinity reagents

Abstract Lysine methylation modulates the function of histone and non-histone proteins, and the enzymes that add or remove lysine methylation—lysine methyltransferases (KMTs) and lysine demethylases (KDMs), respectively—are frequently mutated and dysregulated in human diseases. Identification of lys...

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Bibliographic Details
Main Authors: Christine A. Berryhill, Jocelyne N. Hanquier, Emma H. Doud, Eric Cordeiro-Spinetti, Bradley M. Dickson, Scott B. Rothbart, Amber L. Mosley, Evan M. Cornett
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-27175-x