Complete versus culprit-only revascularization in non-ST-segment elevation myocardial infarction and multivessel coronary artery disease
Introduction/Objective. The optimal percutaneous coronary intervention (PCI) in patients with non-STelevated myocardial infarction (NSTEMI) and multivessel coronary artery disease (CAD) is still not clear. The aim of our study was to examine intrahospital and long-term major adverse cardiovascular a...
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| Format: | Article |
| Language: | English |
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Serbian Medical Society
2023-01-01
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| Series: | Srpski Arhiv za Celokupno Lekarstvo |
| Subjects: | |
| Online Access: | https://doiserbia.nb.rs/img/doi/0370-8179/2023/0370-81792300002J.pdf |
| _version_ | 1797807515466989568 |
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| author | Jaraković Milana Petrović Milovan Ivanišević Dragan Mihajlović Bojan Kovačević Mila Popov Iva |
| author_facet | Jaraković Milana Petrović Milovan Ivanišević Dragan Mihajlović Bojan Kovačević Mila Popov Iva |
| author_sort | Jaraković Milana |
| collection | DOAJ |
| description | Introduction/Objective. The optimal percutaneous coronary intervention (PCI) in patients with non-STelevated myocardial infarction (NSTEMI) and multivessel coronary artery disease (CAD) is still not clear. The aim of our study was to examine intrahospital and long-term major adverse cardiovascular and cerebrovascular events (MACCE) in this group of patients. Methods. This retrospective study included 225 patients with NSTEMI and multivessel CAD treated with PCI at the Institute of Cardiovascular Diseases of Vojvodina. Three groups were formed: complete one-stage PCI; complete multi-stage PCI, and culprit-only PCI. We analyzed intrahospital and one-year follow-up MACCE and mortality after three years in all three groups. Results. Complete one-stage PCI was performed in 112 (49.8%), complete multi-stage PCI in 70 (31.3%), and culprit-only PCI in 43 (19.1%) patients. Patients with multi-stage complete PCI had the lowest mortality in comparison with one-stage and culprit-only PCI, both intrahospital (0% vs. 0.9% and 20.9%, respectively, p < 0.0005) and after one year (0% vs. 2.7% and 30.2%, respectively, p < 0.0005) and three years (4.3% vs. 5.4% and 32.6%, respectively, p < 0.0005). There was no significant difference in other MACCE between the groups, both intrahospital and after one year. Conclusion. In our study, multi-stage PCI significantly reduces intrahospital, one-year and three-year follow-up mortality in patients with NSTEMI and multivessel CAD. |
| first_indexed | 2024-03-13T06:24:42Z |
| format | Article |
| id | doaj.art-6312211bbf3849218b9a1047045d6d94 |
| institution | Directory Open Access Journal |
| issn | 0370-8179 2406-0895 |
| language | English |
| last_indexed | 2024-03-13T06:24:42Z |
| publishDate | 2023-01-01 |
| publisher | Serbian Medical Society |
| record_format | Article |
| series | Srpski Arhiv za Celokupno Lekarstvo |
| spelling | doaj.art-6312211bbf3849218b9a1047045d6d942023-06-09T10:43:47ZengSerbian Medical SocietySrpski Arhiv za Celokupno Lekarstvo0370-81792406-08952023-01-011513-417217810.2298/SARH220210002J0370-81792300002JComplete versus culprit-only revascularization in non-ST-segment elevation myocardial infarction and multivessel coronary artery diseaseJaraković Milana0https://orcid.org/0000-0001-8774-1810Petrović Milovan1https://orcid.org/0000-0003-2251-0135Ivanišević Dragan2Mihajlović Bojan3Kovačević Mila4https://orcid.org/0000-0001-9225-5411Popov Iva5Institute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica, Serbia + University of Novi Sad, Faculty of Medicine, Novi Sad, SerbiaInstitute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica, Serbia + University of Novi Sad, Faculty of Medicine, Novi Sad, SerbiaClinic for Cardiac Surgery, University Clinical Center of Serbia, Belgrade, SerbiaInstitute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica, Serbia + University of Novi Sad, Faculty of Medicine, Novi Sad, SerbiaInstitute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica, Serbia + University of Novi Sad, Faculty of Medicine, Novi Sad, SerbiaInstitute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica, SerbiaIntroduction/Objective. The optimal percutaneous coronary intervention (PCI) in patients with non-STelevated myocardial infarction (NSTEMI) and multivessel coronary artery disease (CAD) is still not clear. The aim of our study was to examine intrahospital and long-term major adverse cardiovascular and cerebrovascular events (MACCE) in this group of patients. Methods. This retrospective study included 225 patients with NSTEMI and multivessel CAD treated with PCI at the Institute of Cardiovascular Diseases of Vojvodina. Three groups were formed: complete one-stage PCI; complete multi-stage PCI, and culprit-only PCI. We analyzed intrahospital and one-year follow-up MACCE and mortality after three years in all three groups. Results. Complete one-stage PCI was performed in 112 (49.8%), complete multi-stage PCI in 70 (31.3%), and culprit-only PCI in 43 (19.1%) patients. Patients with multi-stage complete PCI had the lowest mortality in comparison with one-stage and culprit-only PCI, both intrahospital (0% vs. 0.9% and 20.9%, respectively, p < 0.0005) and after one year (0% vs. 2.7% and 30.2%, respectively, p < 0.0005) and three years (4.3% vs. 5.4% and 32.6%, respectively, p < 0.0005). There was no significant difference in other MACCE between the groups, both intrahospital and after one year. Conclusion. In our study, multi-stage PCI significantly reduces intrahospital, one-year and three-year follow-up mortality in patients with NSTEMI and multivessel CAD.https://doiserbia.nb.rs/img/doi/0370-8179/2023/0370-81792300002J.pdfnon-st elevated myocardial infarctionmultivessel coronary artery diseasepercutaneous coronary interventionmajor adverse cardiovascular and cerebrovascular eventsmortality |
| spellingShingle | Jaraković Milana Petrović Milovan Ivanišević Dragan Mihajlović Bojan Kovačević Mila Popov Iva Complete versus culprit-only revascularization in non-ST-segment elevation myocardial infarction and multivessel coronary artery disease Srpski Arhiv za Celokupno Lekarstvo non-st elevated myocardial infarction multivessel coronary artery disease percutaneous coronary intervention major adverse cardiovascular and cerebrovascular events mortality |
| title | Complete versus culprit-only revascularization in non-ST-segment elevation myocardial infarction and multivessel coronary artery disease |
| title_full | Complete versus culprit-only revascularization in non-ST-segment elevation myocardial infarction and multivessel coronary artery disease |
| title_fullStr | Complete versus culprit-only revascularization in non-ST-segment elevation myocardial infarction and multivessel coronary artery disease |
| title_full_unstemmed | Complete versus culprit-only revascularization in non-ST-segment elevation myocardial infarction and multivessel coronary artery disease |
| title_short | Complete versus culprit-only revascularization in non-ST-segment elevation myocardial infarction and multivessel coronary artery disease |
| title_sort | complete versus culprit only revascularization in non st segment elevation myocardial infarction and multivessel coronary artery disease |
| topic | non-st elevated myocardial infarction multivessel coronary artery disease percutaneous coronary intervention major adverse cardiovascular and cerebrovascular events mortality |
| url | https://doiserbia.nb.rs/img/doi/0370-8179/2023/0370-81792300002J.pdf |
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