Novel GPR120 Agonists with Improved Pharmacokinetic Profiles for the Treatment of Type 2 Diabetes

Novel GPR120 Agonists with Improved Pharmacokinetic Profiles for the Treatment of Type 2 Diabetes

GPR120 is a promising target for the treatment of type 2 diabetes (T2DM), which is activated by free fatty acids (FFAs) and stimulates the release of glucagon-like peptide-1(GLP-1). GLP-1, as an incretin, can enhance glucose-dependent secretion of insulin from pancreatic beta cells and reduce blood...

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Bibliographic Details
Main Authors:	Guoxia Ji, Qinghua Guo, Qidi Xue, Ruifang Kong, Shiben Wang, Kang Lei, Renmin Liu, Xuekun Wang
Format:	Article
Language:	English
Published:	MDPI AG 2021-11-01
Series:	Molecules
Subjects:	GPR120 synthesis type 2 diabetes pharmacokinetic profiles
Online Access:	https://www.mdpi.com/1420-3049/26/22/6907

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