Low-Dose Doxycycline Treatment Normalizes Levels of Some Salivary Metabolites Associated with Oral Microbiota in Patients with Primary Sjögren’s Syndrome

Low-Dose Doxycycline Treatment Normalizes Levels of Some Salivary Metabolites Associated with Oral Microbiota in Patients with Primary Sjögren’s Syndrome

Saliva is a complex oral fluid, and plays a major role in oral health. Primary Sjögren’s syndrome (pSS), as an autoimmune disease that typically causes hyposalivation. In the present study, salivary metabolites were studied from stimulated saliva samples (<i>n</i> = 15) of female patient...

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Bibliographic Details
Main Authors: Maria Herrala, Soile Turunen, Kati Hanhineva, Marko Lehtonen, Jopi J. W. Mikkonen, Hubertus Seitsalo, Reijo Lappalainen, Leo Tjäderhane, Raija K. Niemelä, Tuula Salo, Sami Myllymaa, Arja M. Kullaa, Olli Kärkkäinen
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Metabolites
Subjects:
saliva
Sjögren’s syndrome
metabolomics
hyposalivation
doxycycline
Online Access:https://www.mdpi.com/2218-1989/11/9/595

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