A conserved role for the ESCRT membrane budding complex in LINE retrotransposition.

A conserved role for the ESCRT membrane budding complex in LINE retrotransposition.

Long interspersed nuclear element-1s (LINE-1s, or L1s) are an active family of retrotransposable elements that continue to mutate mammalian genomes. Despite the large contribution of L1 to mammalian genome evolution, we do not know where active L1 particles (particles in the process of retrotranspos...

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Bibliographic Details
Main Authors: Axel V Horn, Ivana Celic, Chun Dong, Irena Martirosyan, Jeffrey S Han
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5478143?pdf=render

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