DHA-Provoked Reduction in Adipogenesis and Glucose Uptake Could Be Mediated by Gps2 Upregulation in Immature 3T3-L1 Cells

DHA-Provoked Reduction in Adipogenesis and Glucose Uptake Could Be Mediated by Gps2 Upregulation in Immature 3T3-L1 Cells

The signaling pathway of fatty acids in the context of obesity is an extensively explored topic, yet their primary mechanism of action remains incompletely understood. This study aims to examine the effect of docosahexaenoic acid (DHA) on some crucial aspects of adipogenesis in differentiating 3T3-L...

Full description

Bibliographic Details
Main Authors:	Natalia Grigorova, Zhenya Ivanova, Ekaterina Vachkova, Valeria Petrova, Toncho Penev
Format:	Article
Language:	English
Published:	MDPI AG 2023-08-01
Series:	International Journal of Molecular Sciences
Subjects:	docosahexaenoic acid (DHA) cell viability adipogenesis lipolysis rate glucose uptake Pparg
Online Access:	https://www.mdpi.com/1422-0067/24/17/13325

Similar Items

The Role of Peroxisome Proliferator-Activated Receptor Gamma (PPARG) in Adipogenesis: Applying Knowledge from the Fish Aquaculture Industry to Biomedical Research
by: Rebecca Wafer, et al.
Published: (2017-05-01)

Effects of Chrysoeriol on Adipogenesis and Lipolysis in 3T3-L1 Adipocytes
by: Jinhee Song, et al.
Published: (2022-12-01)

Role of GABA and its receptors in anti-adipogenesis in cultured adipocytes
by: Kanittaporn Trisat, et al.
Published: (2020-10-01)

The Obesity-Susceptibility Gene TMEM18 Promotes Adipogenesis through Activation of PPARG
by: Kathrin Landgraf, et al.
Published: (2020-10-01)

Lablab purpureus (L) bean flour ameliorates plasma proteins and accretion of docosahexaenoic acid (DHA, 22:6, ω‐3) in the plasma, liver, and brain of malnourished rats
by: Shahdat Hossain, et al.
Published: (2020-06-01)

Two-level factorial analysis of the effect of fructose on DHA biosynthetic capacity of Aurantiochytrium sp. SW1
by: Vidyah Manikan, et al.
Published: (2021-01-01)

What Is the Evidence for Dietary-Induced DHA Deficiency in Human Brains?
by: Andrew J. Sinclair, et al.
Published: (2022-12-01)

The role of docosahexaenoic acid in neuronal development and the importance of DHA supplementation during pregnancy
by: Aleksandra Karmańska, et al.
Published: (2023-10-01)

Algal-oil supplements are a viable alternative to fish-oil supplements in terms of docosahexaenoic acid (22:6n-3; DHA)
by: Lisa Ryan, et al.
Published: (2015-12-01)

<i>Clitoria ternatea</i> Flower Petal Extract Inhibits Adipogenesis and Lipid Accumulation in 3T3-L1 Preadipocytes by Downregulating Adipogenic Gene Expression
by: Poramin Chayaratanasin, et al.
Published: (2019-05-01)

Effects of eicosapentaenoic acid and docosahexaenoic acid on C2C12 cell adipogenesis and inhibition of myotube formation
by: Saeed Ghnaimawi, et al.
Published: (2019-09-01)

Oxidative Stress in Endurance Cycling Is Reduced Dose-Dependently after One Month of Re-Esterified DHA Supplementation
by: Lydia de Salazar, et al.
Published: (2020-11-01)

Efficient Enrichment of Retinal DHA with Dietary Lysophosphatidylcholine-DHA: Potential Application for Retinopathies
by: Dhavamani Sugasini, et al.
Published: (2020-10-01)

Acacetin from Traditionally Used Saussurea involucrata Kar. et Kir. Suppressed Adipogenesis in 3T3-L1 Adipocytes and Attenuated Lipid Accumulation in Obese Mice
by: Chian-Jiun Liou, et al.
Published: (2017-08-01)

Eicosapentaenoic acid provokes stronger in vitro antiadipogenic effect than docosahexaenoic acid in differentiated 3T3-L1 cells
by: E. Vachkova, et al.
Published: (2018-12-01)

Anti-obesity potential of glutinous black rice bran extract: Anti-adipogenesis and lipolysis induction in 3T3-L1 adipocyte model
by: Warathorn Chumchoochart, et al.
Published: (2020-04-01)

Brown Algae <i>Dictyopteris divaricata</i> Attenuates Adipogenesis by Modulating Adipocyte Differentiation and Promoting Lipolysis through Heme Oxygenase-1 Activation in 3T3-L1 Cells
by: Lakshi A. Dayarathne, et al.
Published: (2024-02-01)

Docosahexaenoic acid (DHA) production by Aurantiochytrium limacinum using cassava pulp hydrolysate as an alternative low-cost carbon source
by: Uyun Nurul Aini, et al.
Published: (2022-08-01)

Dietary intake of DHA during pregnancy: a significant gap between the actual intake and current nutritional recommendations
by: Regina Wierzejska, et al.
Published: (2018-12-01)

Peanut Shell Extract and Luteolin Regulate Lipid Metabolism and Induce Browning in 3T3-L1 Adipocytes
by: Wenrui Liu, et al.
Published: (2022-09-01)

Application of the Response Surface Methodology to Optimize the Fermentation Parameters for Enhanced Docosahexaenoic Acid (DHA) Production by Thraustochytrium sp. ATCC 26185
by: Kang Wu, et al.
Published: (2018-04-01)

Anti-obesity effect of extract from fermented Curcuma longa L. through regulation of adipogenesis and lipolysis pathway in high-fat diet-induced obese rats
by: Ji Hye Kim, et al.
Published: (2016-01-01)

Omega-3 PUFA vs. NSAIDs for Preventing Cardiac Inflammation
by: Jiayu Ye, et al.
Published: (2018-10-01)

Maternal DHA intake in mice increased DHA metabolites in the pup brain and ameliorated MeHg-induced behavioral disorder
by: Ami Oguro, et al.
Published: (2023-11-01)

Alcohol abuse and docosahexaenoic acid: Effects on cerebral circulation and neurosurvival
by: Michael A Collins
Published: (2015-01-01)

Anti-obesity potential of natural methylxanthines
by: David F. Carrageta, et al.
Published: (2018-04-01)

<i>Trapa japonica</i> Flerov Extract Prevents Obesity by Regulating Adipogenesis and Lipolysis in Differentiated 3T3-L1 Cells
by: Soo-Jeung Park, et al.
Published: (2021-12-01)

Rhodotorula Strains Isolated from Seawater That Can Biotransform Raw Glycerol into Docosahexaenoic Acid (DHA) and Carotenoids for Animal Nutrition
by: Natalie L. Pino-Maureira, et al.
Published: (2021-03-01)

DHA supplementation: A nutritional strategy to improve prenatal Fe homeostasis and prevent birth outcomes related with Fe-deficiency
by: Javier Diaz-Castro, et al.
Published: (2015-12-01)

New Forms of Neuroactive Phospholipids for DHA Enrichment in Brain
by: Romina Gomes, et al.
Published: (2024-02-01)

In Vitro-Generated Hypertrophic-Like Adipocytes Displaying <i>PPARG</i> Isoforms Unbalance Recapitulate Adipocyte Dysfunctions In Vivo
by: Marianna Aprile, et al.
Published: (2020-05-01)

Co-Administration of Propionate or Protocatechuic Acid Does Not Affect DHA-Specific Transcriptional Effects on Lipid Metabolism in Cultured Hepatic Cells
by: Francesca Danesi, et al.
Published: (2020-09-01)

The Rosiglitazone-Like Effects of Vitexilactone, a Constituent from Vitex trifolia L. in 3T3-L1 Preadipocytes
by: Atsuyoshi Nishina, et al.
Published: (2017-11-01)

Increased Levels of Omega-3 Fatty Acids and DHA Are Linked to Pain Reduction in Rheumatoid Arthritis Patients Treated with Janus Kinase Inhibitors
by: Ching-Kun Chang, et al.
Published: (2021-08-01)

Effect of Maternal Docosahexaenoic Acid (DHA) Supplementation on Offspring Neurodevelopment at 12 Months in India: A Randomized Controlled Trial
by: Shweta Khandelwal, et al.
Published: (2020-10-01)

A Higher Proportion of Eicosapentaenoic Acid (EPA) When Combined with Docosahexaenoic Acid (DHA) in Omega-3 Dietary Supplements Provides Higher Antioxidant Effects in Human Retinal Cells
by: Manuel Saenz de Viteri, et al.
Published: (2020-09-01)

Beneficial Effects of Tea and the Green Tea Catechin Epigallocatechin-3-gallate on Obesity
by: Takuji Suzuki, et al.
Published: (2016-09-01)

Lab-Scale Optimization of <em>Aurantiochytrium</em> sp. Culture Medium for Improved Growth and DHA Production
by: Mafalda Trovão, et al.
Published: (2020-04-01)

Antiobesity effect of Kaempferia parviflora accompanied by inhibition of lipogenesis and stimulation of lipolysis
by: Seong-Hoo Park, et al.
Published: (2023-07-01)

Sunflower (Helianthus annuus) seed extract suppresses the lipogenesis pathway and stimulates the lipolysis pathway in high-fat diet-induced obese mice
by: Jeong Moon Yun, et al.
Published: (2022-06-01)