Insights into lipid metabolism and immune-inflammatory responses in the pathogenesis of coronary artery ectasia
Coronary artery ectasia (CAE) is a rare finding that is associated with poor clinical outcomes (Kawsara et al. 2018), and disorders in lipid metabolism have been reported in CAE. Lipids constitute one of the three metabolite types that regulate bodily functions and are also powerful signaling molecu...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-01-01
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| Series: | Frontiers in Physiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2023.1096991/full |
| _version_ | 1797943713251459072 |
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| author | Li Jiang Wei Wei Sheng Kang Xiao-Lin Li Yu Luo |
| author_facet | Li Jiang Wei Wei Sheng Kang Xiao-Lin Li Yu Luo |
| author_sort | Li Jiang |
| collection | DOAJ |
| description | Coronary artery ectasia (CAE) is a rare finding that is associated with poor clinical outcomes (Kawsara et al. 2018), and disorders in lipid metabolism have been reported in CAE. Lipids constitute one of the three metabolite types that regulate bodily functions and are also powerful signaling molecules (Han 2016; Zhu et al. 2021) that affect immunoregulation and inflammatory responses via a series of transcription factors and signaling pathways (Barrera et al. 2013). Although abnormal lipid metabolism and immunoinflammatory responses have been reported in CAE, their roles in the pathogenic mechanisms underlying CAE are currently unclear. |
| first_indexed | 2024-04-10T20:27:26Z |
| format | Article |
| id | doaj.art-631dbfb681aa4bdfa901b7417caca354 |
| institution | Directory Open Access Journal |
| issn | 1664-042X |
| language | English |
| last_indexed | 2024-04-10T20:27:26Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Physiology |
| spelling | doaj.art-631dbfb681aa4bdfa901b7417caca3542023-01-25T08:02:08ZengFrontiers Media S.A.Frontiers in Physiology1664-042X2023-01-011410.3389/fphys.2023.10969911096991Insights into lipid metabolism and immune-inflammatory responses in the pathogenesis of coronary artery ectasiaLi Jiang0Wei Wei1Sheng Kang2Xiao-Lin Li3Yu Luo4Department of Cardiovascular Medicine, East Hospital, Tongji University School of Medicine, Shanghai, ChinaDepartment of Cardiovascular Medicine, East Hospital, Tongji University School of Medicine, Shanghai, ChinaDepartment of Cardiovascular Medicine, East Hospital, Tongji University School of Medicine, Shanghai, ChinaDepartment of Cardiovascular Medicine, Jian East Hospital, Jinggangshan University School of Medicine, Jiangxi, ChinaDepartment of Cardiovascular Medicine, East Hospital, Tongji University School of Medicine, Shanghai, ChinaCoronary artery ectasia (CAE) is a rare finding that is associated with poor clinical outcomes (Kawsara et al. 2018), and disorders in lipid metabolism have been reported in CAE. Lipids constitute one of the three metabolite types that regulate bodily functions and are also powerful signaling molecules (Han 2016; Zhu et al. 2021) that affect immunoregulation and inflammatory responses via a series of transcription factors and signaling pathways (Barrera et al. 2013). Although abnormal lipid metabolism and immunoinflammatory responses have been reported in CAE, their roles in the pathogenic mechanisms underlying CAE are currently unclear.https://www.frontiersin.org/articles/10.3389/fphys.2023.1096991/fullcoronary artery ectasialipid metabolismcytokineimmune-inflammatory responsepathogenesis |
| spellingShingle | Li Jiang Wei Wei Sheng Kang Xiao-Lin Li Yu Luo Insights into lipid metabolism and immune-inflammatory responses in the pathogenesis of coronary artery ectasia Frontiers in Physiology coronary artery ectasia lipid metabolism cytokine immune-inflammatory response pathogenesis |
| title | Insights into lipid metabolism and immune-inflammatory responses in the pathogenesis of coronary artery ectasia |
| title_full | Insights into lipid metabolism and immune-inflammatory responses in the pathogenesis of coronary artery ectasia |
| title_fullStr | Insights into lipid metabolism and immune-inflammatory responses in the pathogenesis of coronary artery ectasia |
| title_full_unstemmed | Insights into lipid metabolism and immune-inflammatory responses in the pathogenesis of coronary artery ectasia |
| title_short | Insights into lipid metabolism and immune-inflammatory responses in the pathogenesis of coronary artery ectasia |
| title_sort | insights into lipid metabolism and immune inflammatory responses in the pathogenesis of coronary artery ectasia |
| topic | coronary artery ectasia lipid metabolism cytokine immune-inflammatory response pathogenesis |
| url | https://www.frontiersin.org/articles/10.3389/fphys.2023.1096991/full |
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