Model for predicting the vaginal dysbiosis’ severity according to the index of conditionally pathogenic microflora

<p class="NoSpacing">A model for predicting the severity of dysbiosis according to the index of opportunistic pathogenic microflora has been developed. <em>The aim</em> of the study is to identify the most informative indicators that objectively reflect the condition of t...

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Main Authors: O. A. Hruzevskyi, A. M. Venger, V. V. Minukhin
Format: Article
Language:English
Published: Kazimierz Wielki University 2020-07-01
Series:Journal of Education, Health and Sport
Subjects:
Online Access:https://apcz.umk.pl/czasopisma/index.php/JEHS/article/view/33313
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author O. A. Hruzevskyi
A. M. Venger
V. V. Minukhin
author_facet O. A. Hruzevskyi
A. M. Venger
V. V. Minukhin
author_sort O. A. Hruzevskyi
collection DOAJ
description <p class="NoSpacing">A model for predicting the severity of dysbiosis according to the index of opportunistic pathogenic microflora has been developed. <em>The aim</em> of the study is to identify the most informative indicators that objectively reflect the condition of the pathological process and develop a system for predicting the risk of occurrence and severity of dysbiosis behind these indicators. Statistical processing of data was carried out using variational and correlation analysis methods using the Application software package Statistica v.10 (StatSoft, Inc.). At the first stage of the analysis, the index of conditionally pathogenic microflora was considered as a resultant trait. To identify factors that are more associated with the risk of developing dysbiosis with IOPM, a selection of significant traits was performed using a genetic selection algorithm. The prediction of the severity of dysbiosis with IOPM was considered. The nine factor attributes obtained with the help of mathematical analysis allowed to predict the severity of vaginal dysbiosis with high accuracy and to calculate the IOPM indices. Phasal nature of development of the immune system reaction during the development of vaginal dysbiosis is revealed. Possibility of practical use of the developed model is shown.</p>
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spelling doaj.art-63208d3557e2482496cb0fbdffeae2372022-12-21T22:37:19ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062020-07-0110745646410.12775/JEHS.2020.10.07.04726784Model for predicting the vaginal dysbiosis’ severity according to the index of conditionally pathogenic microfloraO. A. Hruzevskyi0A. M. Venger1V. V. Minukhin2Odesa National Medical University Ministry of Health of UkraineOdesa National Medical University Ministry of Health of UkraineI. I. Mechnikoff Institute of Microbiology and Immunology of National Academy of Medical Science of Ukraine<p class="NoSpacing">A model for predicting the severity of dysbiosis according to the index of opportunistic pathogenic microflora has been developed. <em>The aim</em> of the study is to identify the most informative indicators that objectively reflect the condition of the pathological process and develop a system for predicting the risk of occurrence and severity of dysbiosis behind these indicators. Statistical processing of data was carried out using variational and correlation analysis methods using the Application software package Statistica v.10 (StatSoft, Inc.). At the first stage of the analysis, the index of conditionally pathogenic microflora was considered as a resultant trait. To identify factors that are more associated with the risk of developing dysbiosis with IOPM, a selection of significant traits was performed using a genetic selection algorithm. The prediction of the severity of dysbiosis with IOPM was considered. The nine factor attributes obtained with the help of mathematical analysis allowed to predict the severity of vaginal dysbiosis with high accuracy and to calculate the IOPM indices. Phasal nature of development of the immune system reaction during the development of vaginal dysbiosis is revealed. Possibility of practical use of the developed model is shown.</p>https://apcz.umk.pl/czasopisma/index.php/JEHS/article/view/33313index of opportunistic pathogenic microfloranormobiotaprediction modeldysbiosis
spellingShingle O. A. Hruzevskyi
A. M. Venger
V. V. Minukhin
Model for predicting the vaginal dysbiosis’ severity according to the index of conditionally pathogenic microflora
Journal of Education, Health and Sport
index of opportunistic pathogenic microflora
normobiota
prediction model
dysbiosis
title Model for predicting the vaginal dysbiosis’ severity according to the index of conditionally pathogenic microflora
title_full Model for predicting the vaginal dysbiosis’ severity according to the index of conditionally pathogenic microflora
title_fullStr Model for predicting the vaginal dysbiosis’ severity according to the index of conditionally pathogenic microflora
title_full_unstemmed Model for predicting the vaginal dysbiosis’ severity according to the index of conditionally pathogenic microflora
title_short Model for predicting the vaginal dysbiosis’ severity according to the index of conditionally pathogenic microflora
title_sort model for predicting the vaginal dysbiosis severity according to the index of conditionally pathogenic microflora
topic index of opportunistic pathogenic microflora
normobiota
prediction model
dysbiosis
url https://apcz.umk.pl/czasopisma/index.php/JEHS/article/view/33313
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AT vvminukhin modelforpredictingthevaginaldysbiosisseverityaccordingtotheindexofconditionallypathogenicmicroflora