The chemistry and efficacy benefits of polysaccharides from Atractylodes macrocephala Koidz
Atractylodes macrocephala Koidz (AM), traditional Chinese medicine (TCM) with many medicinal values, has a long usage history in China and other oriental countries. The phytochemical investigation revealed the presence of volatile oils, polysaccharides, lactones, flavonoids, and others. The polysacc...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-08-01
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| Series: | Frontiers in Pharmacology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2022.952061/full |
| _version_ | 1817999397222350848 |
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| author | Congying Liu Shengguang Wang Zedong Xiang Tong Xu Mengyuan He Qing Xue Huaying Song Peng Gao Zhufeng Cong |
| author_facet | Congying Liu Shengguang Wang Zedong Xiang Tong Xu Mengyuan He Qing Xue Huaying Song Peng Gao Zhufeng Cong |
| author_sort | Congying Liu |
| collection | DOAJ |
| description | Atractylodes macrocephala Koidz (AM), traditional Chinese medicine (TCM) with many medicinal values, has a long usage history in China and other oriental countries. The phytochemical investigation revealed the presence of volatile oils, polysaccharides, lactones, flavonoids, and others. The polysaccharides from AM are important medicinal components, mainly composed of glucose (Glc), galactose (Gal), rhamnose (Rha), arabinose (Ara), mannose (Man), galacturonic acid (GalA) and xylose (Xyl). It also showed valuable bioactivities, such as immunomodulatory, antitumour, gastroprotective and intestinal health-promoting, hepatoprotective, hypoglycaemic as well as other activities. At the same time, based on its special structure and pharmacological activity, it can also be used as immune adjuvant, natural plant supplement and vaccine adjuvant. The aim of this review is to summarize and critically analyze up-to-data on the chemical compositions, biological activities and applications of polysaccharide from AM based on scientific literatures in recent years. |
| first_indexed | 2024-04-14T03:07:02Z |
| format | Article |
| id | doaj.art-6322e9b03b414619b411ec24714d491e |
| institution | Directory Open Access Journal |
| issn | 1663-9812 |
| language | English |
| last_indexed | 2024-04-14T03:07:02Z |
| publishDate | 2022-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj.art-6322e9b03b414619b411ec24714d491e2022-12-22T02:15:41ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122022-08-011310.3389/fphar.2022.952061952061The chemistry and efficacy benefits of polysaccharides from Atractylodes macrocephala KoidzCongying Liu0Shengguang Wang1Zedong Xiang2Tong Xu3Mengyuan He4Qing Xue5Huaying Song6Peng Gao7Zhufeng Cong8College of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, ChinaCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, ChinaCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, ChinaCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, ChinaCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, ChinaCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, ChinaCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, ChinaCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, ChinaShandong First Medical University Affiliated Shandong Tumor Hospital and Institute, Shandong Cancer Hospital and Institute, Jinan, ChinaAtractylodes macrocephala Koidz (AM), traditional Chinese medicine (TCM) with many medicinal values, has a long usage history in China and other oriental countries. The phytochemical investigation revealed the presence of volatile oils, polysaccharides, lactones, flavonoids, and others. The polysaccharides from AM are important medicinal components, mainly composed of glucose (Glc), galactose (Gal), rhamnose (Rha), arabinose (Ara), mannose (Man), galacturonic acid (GalA) and xylose (Xyl). It also showed valuable bioactivities, such as immunomodulatory, antitumour, gastroprotective and intestinal health-promoting, hepatoprotective, hypoglycaemic as well as other activities. At the same time, based on its special structure and pharmacological activity, it can also be used as immune adjuvant, natural plant supplement and vaccine adjuvant. The aim of this review is to summarize and critically analyze up-to-data on the chemical compositions, biological activities and applications of polysaccharide from AM based on scientific literatures in recent years.https://www.frontiersin.org/articles/10.3389/fphar.2022.952061/fullAtractylodes macrocephala Koidz.polysaccharidechemical compositionbiological activityapplication |
| spellingShingle | Congying Liu Shengguang Wang Zedong Xiang Tong Xu Mengyuan He Qing Xue Huaying Song Peng Gao Zhufeng Cong The chemistry and efficacy benefits of polysaccharides from Atractylodes macrocephala Koidz Frontiers in Pharmacology Atractylodes macrocephala Koidz. polysaccharide chemical composition biological activity application |
| title | The chemistry and efficacy benefits of polysaccharides from Atractylodes macrocephala Koidz |
| title_full | The chemistry and efficacy benefits of polysaccharides from Atractylodes macrocephala Koidz |
| title_fullStr | The chemistry and efficacy benefits of polysaccharides from Atractylodes macrocephala Koidz |
| title_full_unstemmed | The chemistry and efficacy benefits of polysaccharides from Atractylodes macrocephala Koidz |
| title_short | The chemistry and efficacy benefits of polysaccharides from Atractylodes macrocephala Koidz |
| title_sort | chemistry and efficacy benefits of polysaccharides from atractylodes macrocephala koidz |
| topic | Atractylodes macrocephala Koidz. polysaccharide chemical composition biological activity application |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2022.952061/full |
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