Global Illness and Deaths Caused by Rotavirus Disease in Children

To estimate the global illness and deaths caused by rotavirus disease, we reviewed studies published from 1986 to 2000 on deaths caused by diarrhea and on rotavirus infections in children. We assessed rotavirus-associated illness in three clinical settings (mild cases requiring home care alone, mode...

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Main Authors: Umesh D. Parashar, Erik G. Hummelman, Joseph S. Bresee, Mark A. Miller, Roger I. Glass
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2003-05-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/9/5/02-0562_article
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author Umesh D. Parashar
Erik G. Hummelman
Joseph S. Bresee
Mark A. Miller
Roger I. Glass
author_facet Umesh D. Parashar
Erik G. Hummelman
Joseph S. Bresee
Mark A. Miller
Roger I. Glass
author_sort Umesh D. Parashar
collection DOAJ
description To estimate the global illness and deaths caused by rotavirus disease, we reviewed studies published from 1986 to 2000 on deaths caused by diarrhea and on rotavirus infections in children. We assessed rotavirus-associated illness in three clinical settings (mild cases requiring home care alone, moderate cases requiring a clinic visit, and severe cases requiring hospitalization) and death rates in countries in different World Bank income groups. Each year, rotavirus causes approximately 111 million episodes of gastroenteritis requiring only home care, 25 million clinic visits, 2 million hospitalizations, and 352,000–592,000 deaths (median, 440,000 deaths) in children <5 years of age. By age 5, nearly every child will have an episode of rotavirus gastroenteritis, 1 in 5 will visit a clinic, 1 in 60 will be hospitalized, and approximately 1 in 293 will die. Children in the poorest countries account for 82% of rotavirus deaths. The tremendous incidence of rotavirus disease underscores the urgent need for interventions, such as vaccines, to prevent childhood deaths in developing nations.
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spelling doaj.art-6325d4abe2894496966caf105bc75b0d2022-12-21T23:55:21ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592003-05-019556557210.3201/eid0905.020562Global Illness and Deaths Caused by Rotavirus Disease in ChildrenUmesh D. ParasharErik G. HummelmanJoseph S. BreseeMark A. MillerRoger I. GlassTo estimate the global illness and deaths caused by rotavirus disease, we reviewed studies published from 1986 to 2000 on deaths caused by diarrhea and on rotavirus infections in children. We assessed rotavirus-associated illness in three clinical settings (mild cases requiring home care alone, moderate cases requiring a clinic visit, and severe cases requiring hospitalization) and death rates in countries in different World Bank income groups. Each year, rotavirus causes approximately 111 million episodes of gastroenteritis requiring only home care, 25 million clinic visits, 2 million hospitalizations, and 352,000–592,000 deaths (median, 440,000 deaths) in children <5 years of age. By age 5, nearly every child will have an episode of rotavirus gastroenteritis, 1 in 5 will visit a clinic, 1 in 60 will be hospitalized, and approximately 1 in 293 will die. Children in the poorest countries account for 82% of rotavirus deaths. The tremendous incidence of rotavirus disease underscores the urgent need for interventions, such as vaccines, to prevent childhood deaths in developing nations.https://wwwnc.cdc.gov/eid/article/9/5/02-0562_articledeathsdiarrheadisease burdenhospitalizationsmorbiditymortality
spellingShingle Umesh D. Parashar
Erik G. Hummelman
Joseph S. Bresee
Mark A. Miller
Roger I. Glass
Global Illness and Deaths Caused by Rotavirus Disease in Children
Emerging Infectious Diseases
deaths
diarrhea
disease burden
hospitalizations
morbidity
mortality
title Global Illness and Deaths Caused by Rotavirus Disease in Children
title_full Global Illness and Deaths Caused by Rotavirus Disease in Children
title_fullStr Global Illness and Deaths Caused by Rotavirus Disease in Children
title_full_unstemmed Global Illness and Deaths Caused by Rotavirus Disease in Children
title_short Global Illness and Deaths Caused by Rotavirus Disease in Children
title_sort global illness and deaths caused by rotavirus disease in children
topic deaths
diarrhea
disease burden
hospitalizations
morbidity
mortality
url https://wwwnc.cdc.gov/eid/article/9/5/02-0562_article
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