CYP2C8, PTGS-1, 2 gene polymorphisms prevalence associated with sensitivity to non-steroidal anti-inflammatory drugs among North Caucasus ethnic groups

CYP2C8, PTGS-1, 2 gene polymorphisms prevalence associated with sensitivity to non-steroidal anti-inflammatory drugs among North Caucasus ethnic groups

Aim. Find the prevalence of CYP2C8*3 (rs10509681; rs11572080), PTGS-1 (rs10306135; rs12353214) and PTGS-2 (rs20417) alleles and genotypes in four ethnic groups among Laks, Avars, Dargins and Kumyks. Materials and methods. The study involved 400 volunteers from four ethnic groups living in Republi...

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Bibliographic Details
Main Authors: Sherzod P. Abdullaev, Natalia P. Denisenko, Karin B. Mirzaev, Gregorii N. Shuev, Zhannet A. Sozaeva, Anastasia A. Kachanova, Suleiman N. Mammaev, Elvira A. Kasaeva, Danial M. Gafurov, Elena A. Grishina, Dmitry A. Sychev
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2021-11-01
Series:Терапевтический архив
Subjects:
pharmacogenetics
ethnics
cyp2c8
ptgs-1
ptgs-2
non-steroidal anti-inflammatory drugs
Online Access:https://ter-arkhiv.ru/0040-3660/article/viewFile/99612/73074

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