A four-step strategy for handling missing outcome data in randomised trials affected by a pandemic

A four-step strategy for handling missing outcome data in randomised trials affected by a pandemic

Abstract Background The coronavirus pandemic (Covid-19) presents a variety of challenges for ongoing clinical trials, including an inevitably higher rate of missing outcome data, with new and non-standard reasons for missingness. International drug trial guidelines recommend trialists review plans f...

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Bibliographic Details
Main Authors: Suzie Cro, Tim P. Morris, Brennan C. Kahan, Victoria R. Cornelius, James R. Carpenter
Format: Article
Language:English
Published: BMC 2020-08-01
Series:BMC Medical Research Methodology
Subjects:
Missing data
Pandemic
Coronavirus SARS-CoV-2
Covid-19
Randomised trials
Estimands
Online Access:http://link.springer.com/article/10.1186/s12874-020-01089-6

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