Facial recontouring with autologous cryopreserved fat graft

Background: Autologous fat graft is a well established technique for soft tissue augmentation and the most significant drawback remains the unpredictability of the absorption rate and the possible repeating fat harvest procedures. In our basic study, we found evidence to support that fat cryopreserv...

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Main Authors: Hsu Ma, Yin-Han Fang, Chih-Hsun Lin, Cherng-Kang Perng, Chi-Han Tsai, Fu-Yinn Hsiao
Format: Article
Language:English
Published: Wolters Kluwer Health/LWW 2018-01-01
Series:Formosan Journal of Surgery
Subjects:
Online Access:http://www.e-fjs.org/article.asp?issn=1682-606X;year=2018;volume=51;issue=2;spage=58;epage=62;aulast=Ma
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author Hsu Ma
Yin-Han Fang
Chih-Hsun Lin
Cherng-Kang Perng
Chi-Han Tsai
Fu-Yinn Hsiao
author_facet Hsu Ma
Yin-Han Fang
Chih-Hsun Lin
Cherng-Kang Perng
Chi-Han Tsai
Fu-Yinn Hsiao
author_sort Hsu Ma
collection DOAJ
description Background: Autologous fat graft is a well established technique for soft tissue augmentation and the most significant drawback remains the unpredictability of the absorption rate and the possible repeating fat harvest procedures. In our basic study, we found evidence to support that fat cryopreservation is a practical method of storing fat tissue and several anecdotal clinical experiences suggest its clinical efficacy. Methods: Thirty two patients who received autologous cryopreserved fat grafts for facial deficiencies were retrospectively reviewed. Autologous cryopreserved fat grafts were transplanted for “touch up” or augmentation of other soft tissue deficiencies at least three months after fresh fat grafting, The patients' satisfaction was evaluated by a study-specific questionnaire. Results: 84 autologous fresh fat graft and 178 autologous cryopreserved fat graft procedures for the face were performed in 32 patients. There was no infection, skin retraction, fibrosis or necrosis identified except one patient complained of lump formation in the left upper lid (1/178, 0.6%). The self-assessment questionaaire revealed no statistical difference of effectiveness rating between the fresh and cryopreserved fat grafting results (mean± standard deviation: 8.64±1.09 vs 8.73±0.985; P > 0.05) but there was significant statistical difference of convenience rating between the fresh and cryopreserved fat grafting (mean± standard deviation: 2.68±1.07 vs 8.41±1.05; P < 0.05). Of the twenty-two patients who returned the questionnaire, all reported willing to have the treatment in the future (9.73±0.456) and all said that they would like to recommend this treatment to their friends (9.82±0.395). Conclusions: Autologous cryopreserved fat graft is a safe, simple, and convenient technique to restore facial soft tissue defects with acceptable patient satisfaction rate. Clinical Question/Level of Evidence: Therapeutic, IV.
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spelling doaj.art-633703472aed403dadf9707b1c0eae2c2023-09-03T08:38:59ZengWolters Kluwer Health/LWWFormosan Journal of Surgery1682-606X2018-01-01512586210.4103/fjs.fjs_85_17Facial recontouring with autologous cryopreserved fat graftHsu MaYin-Han FangChih-Hsun LinCherng-Kang PerngChi-Han TsaiFu-Yinn HsiaoBackground: Autologous fat graft is a well established technique for soft tissue augmentation and the most significant drawback remains the unpredictability of the absorption rate and the possible repeating fat harvest procedures. In our basic study, we found evidence to support that fat cryopreservation is a practical method of storing fat tissue and several anecdotal clinical experiences suggest its clinical efficacy. Methods: Thirty two patients who received autologous cryopreserved fat grafts for facial deficiencies were retrospectively reviewed. Autologous cryopreserved fat grafts were transplanted for “touch up” or augmentation of other soft tissue deficiencies at least three months after fresh fat grafting, The patients' satisfaction was evaluated by a study-specific questionnaire. Results: 84 autologous fresh fat graft and 178 autologous cryopreserved fat graft procedures for the face were performed in 32 patients. There was no infection, skin retraction, fibrosis or necrosis identified except one patient complained of lump formation in the left upper lid (1/178, 0.6%). The self-assessment questionaaire revealed no statistical difference of effectiveness rating between the fresh and cryopreserved fat grafting results (mean± standard deviation: 8.64±1.09 vs 8.73±0.985; P > 0.05) but there was significant statistical difference of convenience rating between the fresh and cryopreserved fat grafting (mean± standard deviation: 2.68±1.07 vs 8.41±1.05; P < 0.05). Of the twenty-two patients who returned the questionnaire, all reported willing to have the treatment in the future (9.73±0.456) and all said that they would like to recommend this treatment to their friends (9.82±0.395). Conclusions: Autologous cryopreserved fat graft is a safe, simple, and convenient technique to restore facial soft tissue defects with acceptable patient satisfaction rate. Clinical Question/Level of Evidence: Therapeutic, IV.http://www.e-fjs.org/article.asp?issn=1682-606X;year=2018;volume=51;issue=2;spage=58;epage=62;aulast=MaAutologous fatcryopreserved fat graftfacial recontouring
spellingShingle Hsu Ma
Yin-Han Fang
Chih-Hsun Lin
Cherng-Kang Perng
Chi-Han Tsai
Fu-Yinn Hsiao
Facial recontouring with autologous cryopreserved fat graft
Formosan Journal of Surgery
Autologous fat
cryopreserved fat graft
facial recontouring
title Facial recontouring with autologous cryopreserved fat graft
title_full Facial recontouring with autologous cryopreserved fat graft
title_fullStr Facial recontouring with autologous cryopreserved fat graft
title_full_unstemmed Facial recontouring with autologous cryopreserved fat graft
title_short Facial recontouring with autologous cryopreserved fat graft
title_sort facial recontouring with autologous cryopreserved fat graft
topic Autologous fat
cryopreserved fat graft
facial recontouring
url http://www.e-fjs.org/article.asp?issn=1682-606X;year=2018;volume=51;issue=2;spage=58;epage=62;aulast=Ma
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AT cherngkangperng facialrecontouringwithautologouscryopreservedfatgraft
AT chihantsai facialrecontouringwithautologouscryopreservedfatgraft
AT fuyinnhsiao facialrecontouringwithautologouscryopreservedfatgraft