Facial recontouring with autologous cryopreserved fat graft
Background: Autologous fat graft is a well established technique for soft tissue augmentation and the most significant drawback remains the unpredictability of the absorption rate and the possible repeating fat harvest procedures. In our basic study, we found evidence to support that fat cryopreserv...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Health/LWW
2018-01-01
|
Series: | Formosan Journal of Surgery |
Subjects: | |
Online Access: | http://www.e-fjs.org/article.asp?issn=1682-606X;year=2018;volume=51;issue=2;spage=58;epage=62;aulast=Ma |
_version_ | 1827832399301443584 |
---|---|
author | Hsu Ma Yin-Han Fang Chih-Hsun Lin Cherng-Kang Perng Chi-Han Tsai Fu-Yinn Hsiao |
author_facet | Hsu Ma Yin-Han Fang Chih-Hsun Lin Cherng-Kang Perng Chi-Han Tsai Fu-Yinn Hsiao |
author_sort | Hsu Ma |
collection | DOAJ |
description | Background: Autologous fat graft is a well established technique for soft tissue augmentation and the most significant drawback remains the unpredictability of the absorption rate and the possible repeating fat harvest procedures. In our basic study, we found evidence to support that fat cryopreservation is a practical method of storing fat tissue and several anecdotal clinical experiences suggest its clinical efficacy.
Methods: Thirty two patients who received autologous cryopreserved fat grafts for facial deficiencies were retrospectively reviewed. Autologous cryopreserved fat grafts were transplanted for “touch up” or augmentation of other soft tissue deficiencies at least three months after fresh fat grafting, The patients' satisfaction was evaluated by a study-specific questionnaire.
Results: 84 autologous fresh fat graft and 178 autologous cryopreserved fat graft procedures for the face were performed in 32 patients. There was no infection, skin retraction, fibrosis or necrosis identified except one patient complained of lump formation in the left upper lid (1/178, 0.6%). The self-assessment questionaaire revealed no statistical difference of effectiveness rating between the fresh and cryopreserved fat grafting results (mean± standard deviation: 8.64±1.09 vs 8.73±0.985; P > 0.05) but there was significant statistical difference of convenience rating between the fresh and cryopreserved fat grafting (mean± standard deviation: 2.68±1.07 vs 8.41±1.05; P < 0.05). Of the twenty-two patients who returned the questionnaire, all reported willing to have the treatment in the future (9.73±0.456) and all said that they would like to recommend this treatment to their friends (9.82±0.395).
Conclusions: Autologous cryopreserved fat graft is a safe, simple, and convenient technique to restore facial soft tissue defects with acceptable patient satisfaction rate.
Clinical Question/Level of Evidence: Therapeutic, IV. |
first_indexed | 2024-03-12T05:10:40Z |
format | Article |
id | doaj.art-633703472aed403dadf9707b1c0eae2c |
institution | Directory Open Access Journal |
issn | 1682-606X |
language | English |
last_indexed | 2024-03-12T05:10:40Z |
publishDate | 2018-01-01 |
publisher | Wolters Kluwer Health/LWW |
record_format | Article |
series | Formosan Journal of Surgery |
spelling | doaj.art-633703472aed403dadf9707b1c0eae2c2023-09-03T08:38:59ZengWolters Kluwer Health/LWWFormosan Journal of Surgery1682-606X2018-01-01512586210.4103/fjs.fjs_85_17Facial recontouring with autologous cryopreserved fat graftHsu MaYin-Han FangChih-Hsun LinCherng-Kang PerngChi-Han TsaiFu-Yinn HsiaoBackground: Autologous fat graft is a well established technique for soft tissue augmentation and the most significant drawback remains the unpredictability of the absorption rate and the possible repeating fat harvest procedures. In our basic study, we found evidence to support that fat cryopreservation is a practical method of storing fat tissue and several anecdotal clinical experiences suggest its clinical efficacy. Methods: Thirty two patients who received autologous cryopreserved fat grafts for facial deficiencies were retrospectively reviewed. Autologous cryopreserved fat grafts were transplanted for “touch up” or augmentation of other soft tissue deficiencies at least three months after fresh fat grafting, The patients' satisfaction was evaluated by a study-specific questionnaire. Results: 84 autologous fresh fat graft and 178 autologous cryopreserved fat graft procedures for the face were performed in 32 patients. There was no infection, skin retraction, fibrosis or necrosis identified except one patient complained of lump formation in the left upper lid (1/178, 0.6%). The self-assessment questionaaire revealed no statistical difference of effectiveness rating between the fresh and cryopreserved fat grafting results (mean± standard deviation: 8.64±1.09 vs 8.73±0.985; P > 0.05) but there was significant statistical difference of convenience rating between the fresh and cryopreserved fat grafting (mean± standard deviation: 2.68±1.07 vs 8.41±1.05; P < 0.05). Of the twenty-two patients who returned the questionnaire, all reported willing to have the treatment in the future (9.73±0.456) and all said that they would like to recommend this treatment to their friends (9.82±0.395). Conclusions: Autologous cryopreserved fat graft is a safe, simple, and convenient technique to restore facial soft tissue defects with acceptable patient satisfaction rate. Clinical Question/Level of Evidence: Therapeutic, IV.http://www.e-fjs.org/article.asp?issn=1682-606X;year=2018;volume=51;issue=2;spage=58;epage=62;aulast=MaAutologous fatcryopreserved fat graftfacial recontouring |
spellingShingle | Hsu Ma Yin-Han Fang Chih-Hsun Lin Cherng-Kang Perng Chi-Han Tsai Fu-Yinn Hsiao Facial recontouring with autologous cryopreserved fat graft Formosan Journal of Surgery Autologous fat cryopreserved fat graft facial recontouring |
title | Facial recontouring with autologous cryopreserved fat graft |
title_full | Facial recontouring with autologous cryopreserved fat graft |
title_fullStr | Facial recontouring with autologous cryopreserved fat graft |
title_full_unstemmed | Facial recontouring with autologous cryopreserved fat graft |
title_short | Facial recontouring with autologous cryopreserved fat graft |
title_sort | facial recontouring with autologous cryopreserved fat graft |
topic | Autologous fat cryopreserved fat graft facial recontouring |
url | http://www.e-fjs.org/article.asp?issn=1682-606X;year=2018;volume=51;issue=2;spage=58;epage=62;aulast=Ma |
work_keys_str_mv | AT hsuma facialrecontouringwithautologouscryopreservedfatgraft AT yinhanfang facialrecontouringwithautologouscryopreservedfatgraft AT chihhsunlin facialrecontouringwithautologouscryopreservedfatgraft AT cherngkangperng facialrecontouringwithautologouscryopreservedfatgraft AT chihantsai facialrecontouringwithautologouscryopreservedfatgraft AT fuyinnhsiao facialrecontouringwithautologouscryopreservedfatgraft |