Kappa free light chain and neurofilament light independently predict early multiple sclerosis disease activity—a cohort studyResearch in context

Kappa free light chain and neurofilament light independently predict early multiple sclerosis disease activity—a cohort studyResearch in context

Summary: Background: Inter-individual courses of multiple sclerosis (MS) are extremely variable. The objective of this study was to investigate whether κ-free light chain (κ-FLC) index and serum neurofilament light (sNfL) have an additive predictive value for MS disease activity. Methods: Patients...

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Main Authors: Harald Hegen, Klaus Berek, Gabriel Bsteh, Michael Auer, Patrick Altmann, Franziska Di Pauli, Astrid Grams, Dejan Milosavljevic, Markus Ponleitner, Paulina Poskaite, Christine Schnabl, Sebastian Wurth, Anne Zinganell, Thomas Berger, Janette Walde, Florian Deisenhammer
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:EBioMedicine
Subjects:
Cerebrospinal fluid
Kappa free light chain
Neurofilament light
Multiple sclerosis
Disease activity
Prediction
Online Access:http://www.sciencedirect.com/science/article/pii/S235239642300138X

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