Sterile protection and transmission blockade by a multistage anti-malarial vaccine in the pre-clinical study

Sterile protection and transmission blockade by a multistage anti-malarial vaccine in the pre-clinical study

The Malaria Vaccine Technology Roadmap 2013 (World Health Organization) aims to develop safe and effective vaccines by 2030 that will offer at least 75% protective efficacy against clinical malaria and reduce parasite transmission. Here, we demonstrate a highly effective multistage vaccine against b...

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Bibliographic Details
Main Authors: Mitsuhiro Iyori, Andrew M. Blagborough, Tetsushi Mizuno, Yu-ichi Abe, Mio Nagaoka, Naoto Hori, Iroha Yamagoshi, Dari F. Da, William F. Gregory, Ammar A. Hasyim, Yutaro Yamamoto, Akihiko Sakamoto, Kunitaka Yoshida, Hiroaki Mizukami, Hisatoshi Shida, Shigeto Yoshida
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
malaria
vaccine
plasmodium falciparum
PfCSP
Pfs25
LC16m8Δ
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1005476/full

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